Literature DB >> 493065

[Septicaemia and spontaneous peritonitis in the cirrhotic (author's transl)].

N Clumeck, M Estenne, R Vanhoof, P Reding, A Cornil.   

Abstract

During a five year period 36 episodes of septicaemia in 32 patients with hepatic cirrhosis were documented. This represents 20% of the patients hospitalized with a decompensated cirrhosis and 1.1% of the patients with non decompensated cirrhosis. In patients with decompensated cirrhosis, enteric Gram-negative organisms were most frequently isolated (91% of the cases) and ascitis was infected in one third of the cases. No primary foci of infection were documented. On the contrary patients with a non decompensated cirrhosis had infection mostly with Gram-positive organisms (82%) and foci of infection (skin, throat) were documented in 38% of the cases. Infection by enteric organisms was associated with higher mortality than infection by non enteric organisms (68% vs 28%). Five patients with inappropriate antibiotic treatment died from septic shock. Spontaneous septicaemia and peritonitis are frequent complications if cirrhosis. There are potentially treatable causes of deterioration in the cirrhotic patient, necessitating prompt recognition and treatment.

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Year:  1979        PMID: 493065

Source DB:  PubMed          Journal:  Nouv Presse Med        ISSN: 0301-1518


  2 in total

1.  The pharmacokinetics of ceftriaxone and cefotaxime in cirrhotic patients with ascites.

Authors:  L Hary; M Andrejak; S Leleu; J Orfila; J P Capron
Journal:  Eur J Clin Pharmacol       Date:  1989       Impact factor: 2.953

Review 2.  Problems of bacterial infection in patients with liver disease.

Authors:  R J Wyke
Journal:  Gut       Date:  1987-05       Impact factor: 23.059

  2 in total

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