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Literature DB >> 4926687

Effect of nalidixic acid on semionservative replication and repair synthesis after ultraviolet irradiation in Escherichia coli.

Abstract

Both semiconservative deoxyribonucleic acid replication and "extensive repair" synthesis, after ultraviolet irradiation, appear to be blocked by nalidixic acid. These findings suggest that the agent(s) responsible for both of these modes of replication, or some necessary common process or structure, is affected by this drug.

Entities: Chemical Species

Mesh：

Substances：

Year: 1971 PMID： 4926687 PMCID： PMC248517 DOI： 10.1128/jb.105.3.908-912.1971

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

19 in total

1. Efficiency of utilization of thymine and 5-bromouracil for normal and repair DNA synthesis in bacteria.

Authors: L Kanner; P Hanawalt
Journal: Biochim Biophys Acta Date: 1968-05-21

2. DNA transfer and DNA synthesis during bacterial conjugation.

Authors: F Bonhoeffer
Journal: Z Vererbungsl Date: 1966

3. Temperature-sensitive mutants of B. subtilis defective in DNA synthesis.

Authors: J D Gross; D Karamata; P G Hempstead
Journal: Cold Spring Harb Symp Quant Biol Date: 1968

4. Repair replication of DNA in vivo.

Authors: P C Hanawalt; D E Pettijohn; E C Pauling; C F Brunk; D W Smith; L C Kanner; J L Couch
Journal: Cold Spring Harb Symp Quant Biol Date: 1968

5. Thermosensitive mutants of E. coli affected in the processes of DNA synthesis and cellular division.

Authors: Y Hirota; A Ryter; F Jacob
Journal: Cold Spring Harb Symp Quant Biol Date: 1968

6. The implication of repair processes in the mechanism of DNA integration by lymphoma cells.

Authors: S R Ayad; M Fox
Journal: Int J Radiat Biol Relat Stud Phys Chem Med Date: 1969-07

7. Escherichia coli K-12 mutants resistant to nalidixic acid: genetic mapping and dominance studies.

Authors: M W Hane; T H Wood
Journal: J Bacteriol Date: 1969-07 Impact factor: 3.490

8. Mechanism of action of nalidixic acid on Escherichia coli. 3. Conditions required for lethality.

Authors: W H Deitz; T M Cook; W A Goss
Journal: J Bacteriol Date: 1966-02 Impact factor: 3.490

9. Mechanism of action of nalidixic acid on Escherichia coli. Vi. Cell-free studies.

Authors: J V Boyle; T M Cook; W A Goss
Journal: J Bacteriol Date: 1969-01 Impact factor: 3.490

10. Mechanism of action of phenethyl alcohol: breakdown of the cellular permeability barrier.

Authors: S Silver; L Wendt
Journal: J Bacteriol Date: 1967-02 Impact factor: 3.490

8 in total

1. Enhancement by nalidixic acid of the thermal susceptibility of the Ts-7 mutant of Escherichia coli TAU-bar.

Authors: M Nishida; Y Mishima; J Kawada; K L Yielding
Journal: Antimicrob Agents Chemother Date: 1975-09 Impact factor: 5.191

2. Enhancement of post-ultraviolet killing in Escherichia coli K-12 through the action of gyrase inhibitors: evidence for associated gyrase-recBC deoxyribonuclease function.

Authors: M A Purdy; K L Yielding
Journal: Antimicrob Agents Chemother Date: 1979-09 Impact factor: 5.191

Effect of nalidixic acid on semionservative replication and repair synthesis after ultraviolet irradiation in Escherichia coli.

1. Efficiency of utilization of thymine and 5-bromouracil for normal and repair DNA synthesis in bacteria.

2. DNA transfer and DNA synthesis during bacterial conjugation.

3. Temperature-sensitive mutants of B. subtilis defective in DNA synthesis.

4. Repair replication of DNA in vivo.

5. Thermosensitive mutants of E. coli affected in the processes of DNA synthesis and cellular division.

6. The implication of repair processes in the mechanism of DNA integration by lymphoma cells.

7. Escherichia coli K-12 mutants resistant to nalidixic acid: genetic mapping and dominance studies.

8. Mechanism of action of nalidixic acid on Escherichia coli. 3. Conditions required for lethality.

9. Mechanism of action of nalidixic acid on Escherichia coli. Vi. Cell-free studies.

10. Mechanism of action of phenethyl alcohol: breakdown of the cellular permeability barrier.

1. Enhancement by nalidixic acid of the thermal susceptibility of the Ts-7 mutant of Escherichia coli TAU-bar.

2. Enhancement of post-ultraviolet killing in Escherichia coli K-12 through the action of gyrase inhibitors: evidence for associated gyrase-recBC deoxyribonuclease function.

3. Survival of recombination-deficient mutants of Escherichia coli during incubation with nalidixic acid.

4. DNA replication and proteins that bind to DNA.

5. Action of Nalidixic Acid on Chloroplast Replication in Euglena gracilis.

6. Nalidixic acid-induced protein alterations in Escherichia coli.

7. Vitamin B 6 -responsive histidine deficiency in mutants of Salmonella typhimurium.

8. Nalidixic acid inhibition of post-ultraviolet recovery in Escherichia coli K-12: requirement for recBC function.