| Literature DB >> 4925937 |
C Paul, A Shimizu, H Köhler, F W Putnam.
Abstract
The amino acid sequence around the central disulfide bridge linking the mu heavy chains of the human immunoglobulin M monomer is unlike that in immunoglobulin G. This hinge area contains one of the five oligosaccharides of the mu chain, is low in proline, and is the site of tryptic cleavage to yield Fabmicro and Fcmicro fragments.Entities:
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Year: 1971 PMID： 4925937 DOI： 10.1126/science.172.3978.69
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728