Literature DB >> 492164

Elongation factor Tu-induced conformational changes of ribosomes detected by iodination.

O Martinez, J Modolell.   

Abstract

The effect of elongation factor (EF) Tu, bound to the ribosome with the help of poly(uridylic) acid, Phe-tRNA and guanyl-5'-yl methylene diphosphonate, on the conformation and/or chemical environment of ribosomal proteins has been examined using, as a probe, protein iodination. Ribosomes complexed only with poly(uridylic acid) and Phe-tRNA have been used as a control. EF-Tu on the ribosome significantly increases the iodination of proteins S7, S10 and L3 and decreases that of S21 and L18.

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Year:  1979        PMID： 492164     DOI： 10.1007/bf00778423

Source DB:  PubMed          Journal:  Mol Biol Rep        ISSN： 0301-4851            Impact factor:   2.316


  14 in total

1.  The inhibition of ribosomal translocation by viomycin.

Authors:  J Modolell
Journal:  Eur J Biochem       Date:  1977-12

2.  Evidence that proteins S1, S11 and S21 directly participates in the binding of transfer RNA to the 30S ribosome.

Authors:  T G Fanning; M Cantrell; C Y Shih; G R Craven
Journal:  Nucleic Acids Res       Date:  1978-03       Impact factor: 16.971

3.  The interaction of transfer ribonucleic acid with 50 S ribosomal subunit proteins.

Authors:  M Ustav; R Villems; M Saarma; A Lind
Journal:  FEBS Lett       Date:  1977-11-15       Impact factor: 4.124

4.  Evidence for a conformational change in the 30 S E. coli ribosomal subunit upon formation of 70 S particles.

Authors:  D J Litman; C C Lee; C R Cantor
Journal:  FEBS Lett       Date:  1974-10-15       Impact factor: 4.124

5.  Use of protection of 30S ribosomal proteins by tRNA for functional mapping of the E. coli ribosome.

Authors:  D P Rummel; H F Noller
Journal:  Nat New Biol       Date:  1973-09-19

6.  Investigation of the ribosomal peptidyl transferase center using a photoaffinity label.

Authors:  N Hsiung; S A Reines; C R Cantor
Journal:  J Mol Biol       Date:  1974-10-05       Impact factor: 5.469

7.  Binding of aminoacyl-tRNA to ribosomes promoted by elongation factor Tu. Studies on the role of GTP hydrolysis.

Authors:  H Yokosawa; M Kawakita; K Arai; N Inoue-Yokosawa; Y Kaziro
Journal:  J Biochem       Date:  1975-04       Impact factor: 3.387

8.  The protein neighborhood of ribosome-bound elongation factor Tu.

Authors:  C San José; C G Kurland; G Stöffler
Journal:  FEBS Lett       Date:  1976-11-15       Impact factor: 4.124

9.  RNA CODEWORDS AND PROTEIN SYNTHESIS. THE EFFECT OF TRINUCLEOTIDES UPON THE BINDING OF SRNA TO RIBOSOMES.

Authors:  M NIRENBERG; P LEDER
Journal:  Science       Date:  1964-09-25       Impact factor: 47.728

10.  Function of individual 30S subunit proteins of Escherichia coli. Effect of specific immunoglobulin fragments (Fab) on activities of ribosomal decoding sites.

Authors:  J C Lelong; D Gros; F Gros; A Bollen; R Maschler; G Stöffler
Journal:  Proc Natl Acad Sci U S A       Date:  1974-02       Impact factor: 11.205
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