The effect of penicillin, dihydrostreptomycin and prednisolone treatment of experimental Candida krusei infections of the mammary glands of dairy cattle.

The growth of Candida krusei in quarters treated intramammary with penicillin, dihydrostreptomycin and prednisolone was compared with growth in untreated quarters. No clinical mastitis occurred in any of the quarters of either group. The number of yeast organisms isolated from the quarter during and after the treatment period appeared similar in both groups. The number of leukocytes in all treated quarters increased during the antibiotic and steroid treatment period but the number of yeast isolated remained the same or decreased as compared to the control quarters.