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Literature DB >> 4919554

Treatment of menorrhagia with tranexamic acid. A double-blind trial.

Abstract

In a double-blind trial tranexamic acid (Cyclokapron) 1 g. four times a day for the first four days of menstruation, significantly decreased menstrual blood loss in women with menorrhagia for which no organic cause had been found. No difference in side-effects was noted between the active and placebo treatment.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1970 PMID： 4919554 PMCID： PMC1819762 DOI： 10.1136/bmj.4.5729.214

Source DB: PubMed Journal: Br Med J ISSN： 0007-1447

6 in total

1. Measurement of blood loss by means of a whole-body counter.

Authors: J M Holt; F G Mayet; G T Warner; S T Callender
Journal: Br Med J Date: 1967-10-14

2. A double blind study of the effect of tranexamic acid in essential menorrhagia.

Authors: J Vermylen; M L Verhaegen-Declercq; M Verstraete; F Fierens
Journal: Thromb Diath Haemorrh Date: 1968-12-31

3. Treatment of menorrhagia with epsilon aminocaproic acid. A double blind investigation.

Authors: L Nilsson; G Rybo
Journal: Acta Obstet Gynecol Scand Date: 1965 Impact factor: 3.636

4. A whole-body counter for clinical measurements utilizing the 'shadow shield' technique.

Authors: G T Warner; R Oliver
Journal: Phys Med Biol Date: 1966-01 Impact factor: 3.609

5. Menstrual blood loss--a population study. Variation at different ages and attempts to define normality.

Authors: L Hallberg; A M Högdahl; L Nilsson; G Rybo
Journal: Acta Obstet Gynecol Scand Date: 1966 Impact factor: 3.636

6. EXPERIENCES WITH EPSILON-AMINOCAPROIC ACID (EPSILON-ACA) IN THE TREATMENT OF PROFUSE MENSTRUATION.

Authors: I M NILSSON; S E BJOERKMAN
Journal: Acta Med Scand Date: 1965-04

6 in total

27 in total

Review 1. Managing menorrhagia.

Authors: A Coulter; A Long; J Kelland; S O'Meara; M Sculpher; F Song; T A Sheldon
Journal: Qual Health Care Date: 1995-09

2. Dysfunctional uterine bleeding.

Authors: R F Casper
Journal: Can Fam Physician Date: 1983-04 Impact factor: 3.275

3. A randomized control trial to verify the efficacy of pre-operative intra venous tranexamic Acid in the control of tonsillectomy bleeding.

Authors: Ajay George; Ranjan Kumar; Sanjay Kumar; Sharankumar Shetty
Journal: Indian J Otolaryngol Head Neck Surg Date: 2011-01-11

Treatment of menorrhagia with tranexamic acid. A double-blind trial.

1. Measurement of blood loss by means of a whole-body counter.

2. A double blind study of the effect of tranexamic acid in essential menorrhagia.

3. Treatment of menorrhagia with epsilon aminocaproic acid. A double blind investigation.

4. A whole-body counter for clinical measurements utilizing the 'shadow shield' technique.

5. Menstrual blood loss--a population study. Variation at different ages and attempts to define normality.

6. EXPERIENCES WITH EPSILON-AMINOCAPROIC ACID (EPSILON-ACA) IN THE TREATMENT OF PROFUSE MENSTRUATION.

Review 1. Managing menorrhagia.

2. Dysfunctional uterine bleeding.

3. A randomized control trial to verify the efficacy of pre-operative intra venous tranexamic Acid in the control of tonsillectomy bleeding.

4. Fibrinolytic inhibitors for acute gastric haemorrhage.

5. Management of abnormal bleeding.

6. The treatment of unexplained menorrhagia.

Review 7. Clinical applications of fibrinolytic inhibition in gynaecology.

8. Persistent gastrointestinal bleeding successfully treated with aminocaproic acid.

Review 9. The use of total-body counters for the study of iron metabolism and iron loss.

10. Tranexamic acid and upper gastrointestinal haemorrhage--a double-blind trial.