Literature DB >> 4912447

Alpha-chymotrypsin: a case study of substituent constants and regression analysis in enzymic structure--activity relationships.

C Hansch, E Coats.   

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Year:  1970        PMID: 4912447     DOI: 10.1002/jps.2600590602

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


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  9 in total

1.  Neutralizing positive charges at the surface of a protein lowers its rate of amide hydrogen exchange without altering its structure or increasing its thermostability.

Authors:  Bryan F Shaw; Haribabu Arthanari; Max Narovlyansky; Armando Durazo; Dominique P Frueh; Michael P Pollastri; Andrew Lee; Basar Bilgicer; Steven P Gygi; Gerhard Wagner; George M Whitesides
Journal:  J Am Chem Soc       Date:  2010-11-19       Impact factor: 15.419

2.  Lysine acetylation can generate highly charged enzymes with increased resistance toward irreversible inactivation.

Authors:  Bryan F Shaw; Gregory F Schneider; Basar Bilgiçer; George K Kaufman; John M Neveu; William S Lane; Julian P Whitelegge; George M Whitesides
Journal:  Protein Sci       Date:  2008-05-01       Impact factor: 6.725

3.  Prodrugs of peptides. 13. Stabilization of peptide amides against alpha-chymotrypsin by the prodrug approach.

Authors:  A H Kahns; H Bundgaard
Journal:  Pharm Res       Date:  1991-12       Impact factor: 4.200

4.  Structure-activity relationships of 4-hydroxyalkenals in the conjugation catalysed by mammalian glutathione transferases.

Authors:  U H Danielson; H Esterbauer; B Mannervik
Journal:  Biochem J       Date:  1987-11-01       Impact factor: 3.857

5.  Increasing the net charge and decreasing the hydrophobicity of bovine carbonic anhydrase decreases the rate of denaturation with sodium dodecyl sulfate.

Authors:  Katherine L Gudiksen; Irina Gitlin; Demetri T Moustakas; George M Whitesides
Journal:  Biophys J       Date:  2006-04-14       Impact factor: 4.033

6.  New insights into the binding and catalytic mechanisms of Bacillus thuringiensis lactonase: insights into B. thuringiensis AiiA mechanism.

Authors:  Marc N Charendoff; Halie P Shah; James M Briggs
Journal:  PLoS One       Date:  2013-09-18       Impact factor: 3.240

7.  Parameter and structure-activity data bases: management for maximum utility.

Authors:  A Leo
Journal:  Environ Health Perspect       Date:  1985-09       Impact factor: 9.031

8.  How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA.

Authors:  Jayakrishnan Nandakumar; Elaine R Podell; Thomas R Cech
Journal:  Proc Natl Acad Sci U S A       Date:  2009-12-22       Impact factor: 12.779

9.  Structure-affinity relationships of substrates for the neutral amino acid transport system in rabbit ileum.

Authors:  R L Preston; J F Schaeffer; P F Curran
Journal:  J Gen Physiol       Date:  1974-10       Impact factor: 4.086

  9 in total

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