Induction and repression of L-arabinose isomerase in bacteriophage-infected Salmonella typhimurium.

The induction of l-arabinose isomerase in Salmonella typhimurium (LT2) is repressed on infection with clear plaque forming mutants (C(1) and C(2)) of the temperate phage P22 (C(+)). However, after infection with C(+) leading to lysogeny, there is a temporary repression. During this period, messenger ribonucleic acid (RNA) for l-arabinose isomerase accumulates. DNA-RNA hybridization data suggest that there is transcription of host DNA during the period of repression. Interference at the level of translation might be responsible for the cessation of induced enzyme synthesis.