Literature DB >> 4910373

Endotoxin: stimulation of bone resorption in tissue culture.

E Hausmann, L G Raisz, W A Miller.   

Abstract

Bacterial endotoxins can stimulate the release of previously incorporated calcium-45 and tritiated proline from fetal rat bone in tissue culture. Endotoxin from Bacteroides melaninogenicus, an organism regularly found in the gingival crevice of man, produces a response similar to parathyroid hormone and is effective at doses as low as 0.1 microgram per milliliter. This response is inhibited by serum and dependent upon the presence of albumin. Endotoxins may play a role in the bone loss characteristic of human periodontal disease.

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Year:  1970        PMID： 4910373     DOI： 10.1126/science.168.3933.862

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  39 in total

Review 1.  Pathophysiology of chronic bacterial osteomyelitis. Why do antibiotics fail so often?

Authors:  J Ciampolini; K G Harding
Journal:  Postgrad Med J       Date:  2000-08       Impact factor: 2.401

2.  The hemoglobin receptor protein of porphyromonas gingivalis inhibits receptor activator NF-kappaB ligand-induced osteoclastogenesis from bone marrow macrophages.

Authors:  Yuji Fujimura; Hitoshi Hotokezaka; Naoya Ohara; Mariko Naito; Eiko Sakai; Mamiko Yoshimura; Yuka Narita; Hideki Kitaura; Noriaki Yoshida; Koji Nakayama
Journal:  Infect Immun       Date:  2006-05       Impact factor: 3.441

3.  Studies of the healing of bone grafts, and the incorporation of titanium implants in grafted bone: an experimental animal model.

Authors:  E Liljensten; C Larsson; P Thomsen; G Blomqvist; J M Hirsch; C Wedenberg
Journal:  J Mater Sci Mater Med       Date:  1998-09       Impact factor: 3.896

Review 4.  Bacterially induced bone destruction: mechanisms and misconceptions.

Authors:  S P Nair; S Meghji; M Wilson; K Reddi; P White; B Henderson
Journal:  Infect Immun       Date:  1996-07       Impact factor: 3.441

5.  Quantitative analyses of osteoclast changes in resorbing bone organ cultures.

Authors:  D J Rowe; E Hausmann
Journal:  Calcif Tissue Res       Date:  1977-10-20

6.  Lipopolysaccharide-stimulated osteoclastogenesis is mediated by tumor necrosis factor via its P55 receptor.

Authors:  Y Abu-Amer; F P Ross; J Edwards; S L Teitelbaum
Journal:  J Clin Invest       Date:  1997-09-15       Impact factor: 14.808

7.  Stimulation of bone resorption by inflamed nasal mucosa, dermonecrotic toxin-containing conditioned medium from Pasteurella multocida, and purified dermonecrotic toxin from P. multocida.

Authors:  T G Kimman; C W Löwik; L J van de Wee-Pals; C W Thesingh; P Defize; E M Kamp; O L Bijvoet
Journal:  Infect Immun       Date:  1987-09       Impact factor: 3.441

8.  Black-pigmented Bacteroides spp. in the human oral cavity.

Authors:  J J Zambon; H S Reynolds; J Slots
Journal:  Infect Immun       Date:  1981-04       Impact factor: 3.441

9.  Effects of two bacterial products, muramyl dipeptide and endotoxin, on bone resorption in organ culture.

Authors:  L G Raisz; C Alander; G Eilon; S P Whitehead; K Nuki
Journal:  Calcif Tissue Int       Date:  1982-07       Impact factor: 4.333

10.  Role of bacterial products in periodontitis: immune response in gnotobiotic rats monoinfected with Eikenella corrodens.

Authors:  D A Johnson; U H Behling; C H Lai; M Listgarten; S Socransky; A Nowotny
Journal:  Infect Immun       Date:  1978-01       Impact factor: 3.441
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