Literature DB >> 4905991

Mitotic abnormalities in sea urchin embryos exposed to Dactinomycin.

B I Kiefer, C F Entelis, A A Infante.   

Abstract

Dactinomycin at concentrations of 10, 20, 25, and 50 mug/ml causes mitotic abnormalities in sea urchin embryos. Sister chromosome separation is impaired and anaphase bridges are frequently formed. The result is an unequal distribution of the chromosome complement to daughter cells. Possible explanations are discussed.

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Year:  1969        PMID： 4905991      PMCID： PMC223313          DOI： 10.1073/pnas.64.3.857

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  10 in total

1.  THE MITOTIC BEHAVIOR OF CHROMOSOMES IN ECHINODERM EGGS FOLLOWING INCORPORATION OF BROMODEOXYURIDINE.

Authors:  D MAZIA; M GONTCHAROFF
Journal:  Exp Cell Res       Date:  1964-06       Impact factor: 3.905

2.  MACROMOLECULE SYNTHESIS AND THE INFLUENCE OF ACTINOMYCIN ON EARLY DEVELOPMENT.

Authors:  P R GROSS; G H COUSINEAU
Journal:  Exp Cell Res       Date:  1964-02       Impact factor: 3.905

Review 3.  EFFECTS OF GROWTH-INHIBITING CHEMICALS ON THE SAND-DOLLAR EMBRYO, ECHINARACHNIUS PARMA.

Authors:  D A KARNOFSKY; E B SIMMEL
Journal:  Prog Exp Tumor Res       Date:  1963

4.  Effects of actinomycin D on macromolecule synthesis and early development in sea urchin eggs.

Authors:  P R GROSS; G H COUSINEAU
Journal:  Biochem Biophys Res Commun       Date:  1963-02-18       Impact factor: 3.575

5.  Accumulation of newly synthesized RNA templates in a unique class of polyribosomes during embryogenesis.

Authors:  A A Infante; M Nemer
Journal:  Proc Natl Acad Sci U S A       Date:  1967-08       Impact factor: 11.205

6.  Drugs which affect the structure and function of DNA.

Authors:  M J Waring
Journal:  Nature       Date:  1968-09-28       Impact factor: 49.962

7.  Evidence that the s-polysomes of early sea urchin embryos may be responsible for the synthesis of chromosomal histones.

Authors:  M Nemer; D T Lindsay
Journal:  Biochem Biophys Res Commun       Date:  1969-04-10       Impact factor: 3.575

8.  Messenger RNA in early sea-urchin embryos: size classes.

Authors:  M Nemer; A A Infante
Journal:  Science       Date:  1965-10-08       Impact factor: 47.728

Review 9.  Actinomycin and nucleic acid function.

Authors:  E Reich; I H Goldberg
Journal:  Prog Nucleic Acid Res Mol Biol       Date:  1964

10.  Actinomycin D: uptake by sea urchin eggs and embryos.

Authors:  M M Thaler; M C Cox; C A Villee
Journal:  Science       Date:  1969-05-16       Impact factor: 47.728
  10 in total
  2 in total

1.  Tentacle morphogenesis in hydra : I. The morphological effect of actinomycin D.

Authors:  Georgia E Lesh-Laurie; Leminh Hang
Journal:  Wilhelm Roux Arch Entwickl Mech Org       Date:  1972-12

2.  The effect of puromycin on the early cleavage cycles and morphogenesis of the pond snailLymnaea stagnalis.

Authors:  Elida K Boon-Niermeijer
Journal:  Wilehm Roux Arch Dev Biol       Date:  1975-03
  2 in total

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