Literature DB >> 4902026

Review of the pharmacologic and therapeutic effects of diisopropylammonium dichloroacetate (DIPA).

P W Stacpoole.   

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Year:  1969        PMID: 4902026

Source DB:  PubMed          Journal:  J Clin Pharmacol J New Drugs        ISSN: 0095-9863


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  12 in total

Review 1.  Metabolic modulation of cancer: a new frontier with great translational potential.

Authors:  Adam Kinnaird; Evangelos D Michelakis
Journal:  J Mol Med (Berl)       Date:  2015-01-14       Impact factor: 4.599

Review 2.  Therapeutic applications of dichloroacetate and the role of glutathione transferase zeta-1.

Authors:  Margaret O James; Stephan C Jahn; Guo Zhong; Marci G Smeltz; Zhiwei Hu; Peter W Stacpoole
Journal:  Pharmacol Ther       Date:  2016-10-19       Impact factor: 12.310

3.  Targeting Hypoxia-Inducible Factor-1α/Pyruvate Dehydrogenase Kinase 1 Axis by Dichloroacetate Suppresses Bleomycin-induced Pulmonary Fibrosis.

Authors:  Justin Goodwin; Hyunsung Choi; Meng-Hsiung Hsieh; Michael L Neugent; Jung-Mo Ahn; Heather N Hayenga; Pankaj K Singh; David B Shackelford; In-Kyu Lee; Vladimir Shulaev; Shanta Dhar; Norihiko Takeda; Jung-Whan Kim
Journal:  Am J Respir Cell Mol Biol       Date:  2018-02       Impact factor: 6.914

4.  On-target inhibition of tumor fermentative glycolysis as visualized by hyperpolarized pyruvate.

Authors:  Pankaj Seth; Aaron Grant; Jian Tang; Elena Vinogradov; Xioaen Wang; Robert Lenkinski; Vikas P Sukhatme
Journal:  Neoplasia       Date:  2011-01       Impact factor: 5.715

Review 5.  Pharmacogenetic considerations with dichloroacetate dosing.

Authors:  Margaret O James; Peter W Stacpoole
Journal:  Pharmacogenomics       Date:  2016-05-04       Impact factor: 2.533

Review 6.  Role of dichloroacetate in the treatment of genetic mitochondrial diseases.

Authors:  Peter W Stacpoole; Tracie L Kurtz; Zongchao Han; Taimour Langaee
Journal:  Adv Drug Deliv Rev       Date:  2008-07-04       Impact factor: 15.470

7.  Dichloroacetate Ameliorates Cardiac Dysfunction Caused by Ischemic Insults Through AMPK Signal Pathway-Not Only Shifts Metabolism.

Authors:  Xuan Li; Jia Liu; Haiyan Hu; Shaoxin Lu; Qingguo Lu; Nanhu Quan; Thomas Rousselle; Mulchand S Patel; Ji Li
Journal:  Toxicol Sci       Date:  2019-02-01       Impact factor: 4.849

8.  Synergistic antitumor effect of dichloroacetate in combination with 5-fluorouracil in colorectal cancer.

Authors:  Jingtao Tong; Ganfeng Xie; Jinxia He; Jianjun Li; Feng Pan; Houjie Liang
Journal:  J Biomed Biotechnol       Date:  2011-02-20

9.  Pyruvate dehydrogenase kinase as a novel therapeutic target in oncology.

Authors:  Gopinath Sutendra; Evangelos D Michelakis
Journal:  Front Oncol       Date:  2013-03-07       Impact factor: 6.244

10.  Expression of pyruvate dehydrogenase kinase-1 in gastric cancer as a potential therapeutic target.

Authors:  Hoon Hur; Yi Xuan; Young Bae Kim; Gwang Lee; Wooyoung Shim; Jisoo Yun; In-Hye Ham; Sang-Uk Han
Journal:  Int J Oncol       Date:  2012-11-06       Impact factor: 5.650

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