Literature DB >> 490032

Chloroquine ototoxicity--a reversible phenomenon?

D K Mukherjee.   

Abstract

The case of a six-year-old girl suffering from severe cochleo-vestibular dysfunction following a series of chloroquine phosphate injections is presented in this paper. Prompt institution of therapy with steroids and vaso-dilators has helped to restore the hearing to a serviceable (socially acceptable) level. A surmise is made about the pathogenesis of chloroquine ototoxicity and how prompt appropriate therapy may be able to reverse the process. A plea is made for early referral of these cases so that prompt attention may be paid to them.

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Year:  1979        PMID: 490032     DOI: 10.1017/s0022215100087740

Source DB:  PubMed          Journal:  J Laryngol Otol        ISSN: 0022-2151            Impact factor:   1.469


  11 in total

1.  Adverse reactions to chloroquine and amodiaquine as used for malaria prophylaxis: a review of the literature.

Authors:  R Wittes
Journal:  Can Fam Physician       Date:  1987-11       Impact factor: 3.275

2.  Vestibular disorders among adults in a tertiary hospital in Lagos, Nigeria.

Authors:  O A Somefun; O S Giwa; B A Bamgboye; I Irene Okeke-Igbokwe; A A Abdul Azeez
Journal:  Eur Arch Otorhinolaryngol       Date:  2010-05-13       Impact factor: 2.503

Review 3.  Chloroquine ototoxicity.

Authors:  Rodrigo Bortoli; Mittermayer Santiago
Journal:  Clin Rheumatol       Date:  2007-06-27       Impact factor: 2.980

Review 4.  Experimental, clinical and preventive aspects of ototoxicity.

Authors:  A A Chiodo; P W Alberti
Journal:  Eur Arch Otorhinolaryngol       Date:  1994       Impact factor: 2.503

5.  Severe malaria in children leads to a significant impairment of transitory otoacoustic emissions--a prospective multicenter cohort study.

Authors:  Joachim Schmutzhard; Peter Lackner; Raimund Helbok; Helene Verena Hurth; Fabian Cedric Aregger; Veronika Muigg; Josua Kegele; Sebastian Bunk; Lukas Oberhammer; Natalie Fischer; Leyla Pinggera; Allan Otieno; Bernards Ogutu; Tsiri Agbenyega; Daniel Ansong; Ayola A Adegnika; Saadou Issifou; Patrick Zorowka; Sanjeev Krishna; Benjamin Mordmüller; Erich Schmutzhard; Peter Kremsner
Journal:  BMC Med       Date:  2015-05-28       Impact factor: 8.775

6.  Is Hearing Impairment Associated with Rheumatoid Arthritis? A Review.

Authors:  Amir Emamifar; Kristine Bjoerndal; Inger M J Hansen
Journal:  Open Rheumatol J       Date:  2016-03-15

Review 7.  Clinical Implications of Chloroquine and Hydroxychloroquine Ototoxicity for COVID-19 Treatment: A Mini-Review.

Authors:  Pattarawadee Prayuenyong; Anand V Kasbekar; David M Baguley
Journal:  Front Public Health       Date:  2020-05-29

Review 8.  Systemic toxicity of chloroquine and hydroxychloroquine: prevalence, mechanisms, risk factors, prognostic and screening possibilities.

Authors:  Romain Muller
Journal:  Rheumatol Int       Date:  2021-04-24       Impact factor: 2.631

9.  Reversible audiometric threshold changes in children with uncomplicated malaria.

Authors:  George O Adjei; Bamenla Q Goka; Emmanuel Kitcher; Onike P Rodrigues; Ebenezer Badoe; Jorgen A L Kurtzhals
Journal:  J Trop Med       Date:  2013-03-07

10.  Chloroquine kills hair cells in zebrafish lateral line and murine cochlear cultures: Implications for ototoxicity.

Authors:  Samantha N Davis; Patricia Wu; Esra D Camci; Julian A Simon; Edwin W Rubel; David W Raible
Journal:  Hear Res       Date:  2020-07-08       Impact factor: 3.208

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