Literature DB >> 4896899

Macromolecular finestructure by dark field electron microscopy.

F P Ottensmeyer.   

Abstract

The potential of dark field electron microscopy for examining details of unstained unshadowed macromolecules has been studied. Images produced by scattered electrons show sufficient contrast and resolution to reveal the helical nature of short sections of DNA or the cleft containing the active site in ribonuclease. Spreads of transfer RNA were observed to contain many trifoliate structures.

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Year:  1969        PMID: 4896899      PMCID: PMC1367549          DOI: 10.1016/S0006-3495(69)86441-6

Source DB:  PubMed          Journal:  Biophys J        ISSN: 0006-3495            Impact factor:   4.033


  9 in total

1.  STRUCTURE OF A RIBONUCLEIC ACID.

Authors:  R W HOLLEY; J APGAR; G A EVERETT; J T MADISON; M MARQUISEE; S H MERRILL; J R PENSWICK; A ZAMIR
Journal:  Science       Date:  1965-03-19       Impact factor: 47.728

2.  The sequence of amino acid residues in bovine pancreatic ribonuclease: revisions and confirmations.

Authors:  D G SMYTH; W H STEIN; S MOORE
Journal:  J Biol Chem       Date:  1963-01       Impact factor: 5.157

3.  Determination of base sequence in nucleic acids with the electron microscope: visibility of a marker.

Authors:  M BEER
Journal:  Proc Natl Acad Sci U S A       Date:  1962-03-15       Impact factor: 11.205

4.  Molecular structure of deoxypentose nucleic acids.

Authors:  M H F WILKINS; A R STOKES; H R WILSON
Journal:  Nature       Date:  1953-04-25       Impact factor: 49.962

5.  Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid.

Authors:  J D WATSON; F H CRICK
Journal:  Nature       Date:  1953-04-25       Impact factor: 49.962

6.  Molecular conformations and structure transitions of RNA complementary helices and their possible biological significance.

Authors:  S Arnott; W Fuller; A Hodgson; I Prutton
Journal:  Nature       Date:  1968-11-09       Impact factor: 49.962

7.  Nucleotide sequence of a yeast tyrosine transfer RNA.

Authors:  J T Madison; G A Everett; H Kung
Journal:  Science       Date:  1966-07-29       Impact factor: 47.728

8.  The structure of ribonuclease-S at 3.5 A resolution.

Authors:  H W Wyckoff; K D Hardman; N M Allewell; T Inagami; L N Johnson; F M Richards
Journal:  J Biol Chem       Date:  1967-09-10       Impact factor: 5.157

9.  The structure of ribonuclease-S at 6 A resolution.

Authors:  H W Wyckoff; K D Hardman; N M Allewell; T Inagami; D Tsernoglou; L N Johnson; F M Richards
Journal:  J Biol Chem       Date:  1967-08-25       Impact factor: 5.157

  9 in total
  2 in total

1.  High-resolution shadowing of transfer RNA.

Authors:  R J Abermann; D Yoshikami
Journal:  Proc Natl Acad Sci U S A       Date:  1972-06       Impact factor: 11.205

2.  A study of heavy-light atom discrimination in bright-field electron microscopy using the computer.

Authors:  J Frank
Journal:  Biophys J       Date:  1972-05       Impact factor: 4.033

  2 in total

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