Literature DB >> 4894686

Events occurring during the replication of bacteriophage T4 DNA.

P D Scotti.   

Abstract

Ten temperature-sensitive mutants of T4D have been examined to find the times in the lytic cycle at which a shift to a restrictive temperature no longer exerts a lethal effect. Nine of these mutants play a role in phage DNA synthesis. The results of these experiments suggest that the products of three of the genes tested-genes 42, 44, and 45-have control or complexing functions in addition to any enzymatic ones. The data also indicate that the products of genes 30 and 41 may act cooperatively. The properties of mutants of gene 43 (DNA polymerase) and gene 56 (dCTP-dUTPase) suggest that the production of a certain length of concatameric DNA is necessary before viable phage can be produced.

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Year:  1969        PMID： 4894686      PMCID： PMC223619          DOI： 10.1073/pnas.62.4.1093

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  9 in total

1.  Chromosome structure in phage t4, iii. Terminal redundancy and length determination.

Authors:  G Streisinger; J Emrich; M M Stahl
Journal:  Proc Natl Acad Sci U S A       Date:  1967-02       Impact factor: 11.205

2.  Evidence for a dual role for the bacteriophage T4-induced deoxycytidine triphosphate nucleotidohydrolase.

Authors:  H R Warner; J E Barnes
Journal:  Proc Natl Acad Sci U S A       Date:  1966-10       Impact factor: 11.205

3.  Deoxyribonucleic acid synthesis in Escherichia coli infected with some deoxyribonucleic acid polymerase-less mutants of bacteriophage T4.

Authors:  H R Warner; J E Barnes
Journal:  Virology       Date:  1966-01       Impact factor: 3.616

4.  Distribution of growing points in DNa of bacteriophage T4.

Authors:  R Werner
Journal:  J Mol Biol       Date:  1968-05-14       Impact factor: 5.469

5.  Studies of DNA replication in vivo. 3. Accumulation of a single-stranded isolation product of DNA replication by conditional mutant strains of T4.

Authors:  M Oishi
Journal:  Proc Natl Acad Sci U S A       Date:  1968-07       Impact factor: 11.205

6.  Protein synthesis by Escherichia coli infected with bacteriophage T4D.

Authors:  J Hosoda; C Levinthal
Journal:  Virology       Date:  1968-04       Impact factor: 3.616

7.  Incorporation of uracil-14C into nucleic acids in Escherichia coli infected with bacteriophage T4 and T4 amber mutants.

Authors:  H R Warner; M D Hobbs
Journal:  Virology       Date:  1967-11       Impact factor: 3.616

8.  Enzymatic breakage and joining of deoxyribonucleic acid. II. The structural gene for polynucleotide ligase in bacteriophage T4.

Authors:  G C Fareed; C C Richardson
Journal:  Proc Natl Acad Sci U S A       Date:  1967-08       Impact factor: 11.205

9.  The structural gene for deoxyribonucleic acid polymerase in bacteriophages T4 and T5.

Authors:  A De Waard; A V Paul; I R Lehman
Journal:  Proc Natl Acad Sci U S A       Date:  1965-10       Impact factor: 11.205
  9 in total
  2 in total

1.  Isolation and preliminary characterization of temperature-sensitive mutants of rhizobiophage c.

Authors:  G J Atkins
Journal:  J Virol       Date:  1973-07       Impact factor: 5.103

2.  Temperature-shift analysis of bacteriophage phi 29 gene expression in Bacillus amyloliquefaciens.

Authors:  C F Schachtele; E W Hagen; D L Anderson
Journal:  J Virol       Date:  1971-09       Impact factor: 5.103
  2 in total

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