Literature DB >> 489156

Multicompartment pharmacokinetic analysis and simulations using a programmable calculator.

S Niazi.   

Abstract

This paper describes the use of a programmable calculator (HP-97), for fitting plasma concentration profiles to 1 and 2 compartment open models and calculating fitted and derived parameters together with estimates of steady state plasma drug levels following various dosage regimens in clinical settings.

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Year:  1979        PMID： 489156     DOI： 10.1016/0020-7101(79)90015-1

Source DB:  PubMed          Journal:  Int J Biomed Comput        ISSN： 0020-7101


  3 in total

1.  Effect of multiple administration of orphenadrine or mono-N-desmethylorphenadrine on cytochrome P-450 catalyzed reactions in the rat.

Authors:  A Bast; E M Savenije-Chapel; F A van Kemenade; L W Scheefhals; J Noordhoek
Journal:  Arch Toxicol       Date:  1983-10       Impact factor: 5.153

2.  Plasma levels of doxorubicin after IV bolus injection and infusion of the doxorubicin-DNA complex in rabbits and man. Comparison with free doxorubicin.

Authors:  R Baurain; D Deprez-De Campeneere; A Zenebergh; A Trouet
Journal:  Cancer Chemother Pharmacol       Date:  1982       Impact factor: 3.333

3.  Pharmacokinetics, metabolism and elimination of itanoxone in humans.

Authors:  F E Crawley; R Hyacinthe; P Poitou; A Donath
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1983 Jul-Sep       Impact factor: 2.441
  3 in total

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