| Literature DB >> 489012 |
Abstract
In patients with chromosomal instability and healthy subjects, significant differences were observed in the chromosomal breakage incidence in simultaneous lymphocyte cultures set up with TC medium 199, Eagle's Minimum Essential Medium, or RPMI, or RPMI 1629. The importance of the choice of culture medium for mutagenicity testing and studies of so-called spontaneous breakage is shown. Cultures incubated with TC Medium 199 showed the highest chromosomal breakage incidence.Entities:
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Year: 1979 PMID: 489012 DOI: 10.1007/bf00399393
Source DB: PubMed Journal: Hum Genet ISSN: 0340-6717 Impact factor: 4.132