| Literature DB >> 4887504 |
Abstract
Mutants of Escherichia coli K-12 have been isolated in which several enzymes concerned with tyrosine biosynthesis are derepressed. These mutants were obtained from a parent strain possessing only a single 3-deoxy-d-arabinoheptulosonic acid-7-phosphate (DAHP) synthetase isoenzyme, DAHP synthetase (tyr), by selecting for resistance to the tyrosine analogue, 4-aminophenylalanine. The mutation responsible for this derepression has been mapped and the gene, which is not closely linked to aroF and tyrA, has been designated tyrR.Entities:
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Year: 1969 PMID: 4887504 PMCID: PMC249840 DOI: 10.1128/jb.97.3.1234-1241.1969
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490