Literature DB >> 4883889

Cycasin: detection of associated mutagenic activity in vivo.

M G Gabridge, A Denunzio, M S Legator.   

Abstract

Cycasin and its lagycone, methylazoxymethanol, increase the mutant frequency of Salmonella typhimurium histidine auxotrophs when tested in the hostmediated assay. As expected, the degree of cycasin-related mutagenic activity depends on the facility with which the compound can be enzymatically deglucosylated by the normal intestinal flora.

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Year:  1969        PMID： 4883889     DOI： 10.1126/science.163.3868.689

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  7 in total

1.  [Cancerogenic alkylating substances. 3. Alkyl-halogenides, -sulfates, -sulfonates and strained heterocyclic compounds].

Authors:  H Druckrey; H Kruse; R Preussmann; S Ivankovic; C Landschütz
Journal:  Z Krebsforsch       Date:  1970

Review 2.  Mutagenicity and cytotoxicity of irradiated foods and food components.

Authors:  J Schubert
Journal:  Bull World Health Organ       Date:  1969       Impact factor: 9.408

3.  Activation of cycasin to a mutagen for Saccharomyces cerevisiae by rat intestinal flora.

Authors:  V W Mayer; C J Goin
Journal:  Appl Environ Microbiol       Date:  1983-02       Impact factor: 4.792

Review 4.  [Molecular aspects of carcinogenesis].

Authors:  R Preussmann
Journal:  Langenbecks Arch Chir       Date:  1971-12

5.  Microorganisms as test systems for mutagenicity.

Authors:  G Mohn
Journal:  Arch Toxikol       Date:  1971

6.  DNA fragmentation in some organs of rats and mice treated with cycasin.

Authors:  M Cavanna; S Parodi; M Taningher; C Bolognesi; L Sciabà; G Brambilla
Journal:  Br J Cancer       Date:  1979-04       Impact factor: 7.640

Review 7.  Edible plants containing naturally occurring carcinogens in Japan.

Authors:  I Hirono
Journal:  Jpn J Cancer Res       Date:  1993-10
  7 in total

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