Literature DB >> 4880722

2-Amino-5-(1-methyl-5-nitro-2-imidazolyl)-1,3, 4-thiadiazole: a new antimicrobial agent.

G Berkelhammer, G Asato.   

Abstract

The title compound has been prepared and shown to be highly active against a wide variety of gram-positive and gram-negative bacteria in mice and chicks, as well as against a number of parasitic infections in rodents.

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Year:  1968        PMID： 4880722     DOI： 10.1126/science.162.3858.1146

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  5 in total

Review 1.  Infectious diseases. Annual review of significant publications.

Authors:  H A Reimann
Journal:  Postgrad Med J       Date:  1969-07       Impact factor: 2.401

Review 2.  Functionalized Nitroimidazole Scaffold Construction and Their Pharmaceutical Applications: A 1950-2021 Comprehensive Overview.

Authors:  Ria Gupta; Sumit Sharma; Rohit Singh; Ram A Vishwakarma; Serge Mignani; Parvinder Pal Singh
Journal:  Pharmaceuticals (Basel)       Date:  2022-04-30

3.  Evaluation of genotoxic effects of new molecules with possible trypanocidal activity for Chagas disease treatment.

Authors:  Francisco V C Mello; Alcione S Carvalho; Mônica M Bastos; Nubia Boechat; Claudia A F Aiub; Israel Felzenszwalb
Journal:  ScientificWorldJournal       Date:  2013-11-07

Review 4.  2-Amino-1,3,4-thiadiazole as a potential scaffold for promising antimicrobial agents.

Authors:  Georgeta Serban; Oana Stanasel; Sanda Bota; Eugenia Serban
Journal:  Drug Des Devel Ther       Date:  2018-05-31       Impact factor: 4.162

5.  Failure of fluconazole in treating cutaneous leishmaniasis caused by Leishmania guyanensis in the Brazilian Amazon: An open, nonrandomized phase 2 trial.

Authors:  Valeska Albuquerque Francesconi; Fabio Francesconi; Rajendranath Ramasawmy; Gustavo Adolfo Sierra Romero; Maria das Graças Costa Alecrim
Journal:  PLoS Negl Trop Dis       Date:  2018-02-26
  5 in total

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