Survey of the eventual diagnosis in 226 cases referred for a second histological opinion after an initial biopsy diagnosis of reticulum cell sarcoma.

In a series of 226 cases of lymphadenopathy in which an initial histological diagnosis of reticulum cell sarcoma was reviewed in a reference laboratory this interpretation was confirmed in 165 cases (73%). In the 61 other cases the diagnosis of reticulum cell sarcoma was considered to be mistaken. The conditions most frequently confused with reticulum cell sarcoma were Hodgkin's disease (particularly its ordinary form) and metastatic tumours.