Literature DB >> 4877738

Clinical trial of 6 per cent hydroxyethyl starch (a new plasma expander).

T F Solanke.   

Abstract

No adverse effects were seen in 29 patients given an intravenous infusion of 6% hydroxyethyl starch solution. Platelet counts had fallen by eight hours after infusion, but had reached pretransfusion levels by 24 hours. Two patients developed unusual bleeding post-operatively, which was possibly due to the infusion. Further investigations on the first stage of coagulation and prothrombin generation in patients receiving hydroxyethyl starch are required.

Entities:  

Mesh:

Substances:

Year:  1968        PMID: 4877738      PMCID: PMC1989559          DOI: 10.1136/bmj.3.5621.783

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  10 in total

1.  Hydroxyethyl starch: the Paradigm of Eminence-Based Versus Evidence-Based Medicine-1.

Authors:  Federico Bilotta; Giovanni Giordano; Fabrizio Caroletti; Francesco Pugliese
Journal:  Turk J Anaesthesiol Reanim       Date:  2017-06-01

Review 2.  Effect of molecular weight and substitution on tissue uptake of hydroxyethyl starch: a meta-analysis of clinical studies.

Authors:  Romuald Bellmann; Clemens Feistritzer; Christian J Wiedermann
Journal:  Clin Pharmacokinet       Date:  2012-04-01       Impact factor: 6.447

3.  Urinary excretion kinetics of hydroxyethyl starch 350/0.60 in normovolaemic man.

Authors:  J M Mishler; C R Ricketts; E J Parkhouse
Journal:  J Clin Pathol       Date:  1981-04       Impact factor: 3.411

4.  Changes in the molecular composition of circulating hydroxyethyl starch.

Authors:  S P Farrow; M Hall; C R Ricketts
Journal:  Br J Pharmacol       Date:  1970-04       Impact factor: 8.739

Review 5.  Blood and plasma substitutes--plasma expansion and oxygen transport properties.

Authors:  K Waxman; K K Tremper; G R Mason
Journal:  West J Med       Date:  1985-08

6.  Post-transfusion survival of hydroxyethyl starch 450/0.70 in man: a long-term study.

Authors:  J M Mishler; C R Ricketts; E J Parkhouse
Journal:  J Clin Pathol       Date:  1980-02       Impact factor: 3.411

7.  Changes in the molecular composition of circulating hydroxyethyl starch following consecutive daily infusions in man.

Authors:  J M Mishler; C R Ricketts; E J Parkhouse
Journal:  Br J Clin Pharmacol       Date:  1979-05       Impact factor: 4.335

8.  A clinical study of low molecular weight-hydroxyethyl starch, a new plasma expander.

Authors:  J M Mishler; E S Parry; B A Sutherland; J R Bushrod
Journal:  Br J Clin Pharmacol       Date:  1979-06       Impact factor: 4.335

9.  Hydroxyethyl starch. An agent for hypovolaemic schock treatment II. Urinary excretion in normal volunteers following three consecutive daily infusions.

Authors:  J M Mishler; H Borberg; P M Emerson; R Gross
Journal:  Br J Clin Pharmacol       Date:  1977-10       Impact factor: 4.335

Review 10.  Reporting bias in trials of volume resuscitation with hydroxyethyl starch.

Authors:  Christian J Wiedermann
Journal:  Wien Klin Wochenschr       Date:  2014-03-05       Impact factor: 1.704

  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.