| Literature DB >> 487319 |
R Huxtable, J Azari, T Reisine, P Johnson, H Yamamura, A Barbeau.
Abstract
The distribution of amino acids in two Friedreich's ataxia brains is compared to 4 control brains. Glutamate and GABA were decreased in the cerebellar hemispheres and/or in the vermis. Taurine concentrations were uniformly elevated throughout the areas studied. Taurine/glutamate and taurine/GABA ratios were consistently elevated in Friedreich's ataxia brains, whereas glutamate/glutamine ratios were consistently decreased (with normal glutamine concentrations).Entities:
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Year: 1979 PMID： 487319 DOI： 10.1017/s0317167100119742
Source DB: PubMed Journal: Can J Neurol Sci ISSN： 0317-1671 Impact factor: 2.104