| Literature DB >> 487229 |
R L Knill, P H Manninen, J L Clement.
Abstract
Enflurane sedation and anaesthesia in healthy fit subjects reduced ventilation and the response to carbon dioxide, hypoxaemia and a low dose of doxapram, all in a dose-related fashion. Comparing the three chemoreflexes tested, the response to hypoxaemia and doxapram were the more profoundly impaired; they were nearly totally abolished by anaesthesia. These effects of enflurane on chemoreflex activities are qualitatively similar to those previously observed with halothane.Entities:
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Year: 1979 PMID: 487229 DOI: 10.1007/bf03006447
Source DB: PubMed Journal: Can Anaesth Soc J ISSN: 0008-2856