| Literature DB >> 486466 |
N K Wills, D C Eaton, S A Lewis, M S Ifshin.
Abstract
The polyene antibiotic nystatin is used to reduce selectively to zero the apical membrane resistance of the rabbit descending colon, allowing the measurement of the current-voltage curve of the basolateral membrane. The I--V relationship is described by the Goldman-Hodgkin-Katz equations allowing calculation of PNa/PK, PCl/PK and PK for the basolateral membrane. Cs+ is found to block inward current (serosa to mucosa) in a manner similar to that found in excitable membranes.Entities:
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Year: 1979 PMID： 486466 DOI： 10.1016/0005-2736(79)90405-x
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002