| Literature DB >> 486446 |
S Carnie, J N Israelachvili, B A Pailthorpe.
Abstract
Predictions, based on a previously developed theory, of the radii and asymmetric lipid distribution of mixed phosphatidylcholine/lysophosphatidylcholine and phosphatidylcholine/cholesterol vesicles of variable composition are presented. The results compare well with available experimental data, except for cis-unsaturated phosphatidylcholine/cholesterol vesicles at high concentrations of cholesterol. It is concluded that specific lipid-lipid interactions need not be invoked for saturated and trans-unsaturated phosphatidylcholine mixed with lysophosphatidylcholine or cholesterol. A discussion of the effect of packing stresses on induced flip-flop and non-spherical vesicles is also presented.Entities:
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Year: 1979 PMID: 486446 DOI: 10.1016/0005-2736(79)90375-4
Source DB: PubMed Journal: Biochim Biophys Acta ISSN: 0006-3002