Literature DB >> 486156

Inhibition of human alkaline phosphatases by vanadate.

L E Seargeant, R A Stinson.   

Abstract

Orthovanadate was shown to be a potent competitive inhibitor (Ki less than 1 microM) of purified alkaline phosphatase from human liver, intestine of kidney. Inhibition was reversed and full enzymic activity restored in the presence of 1mM-adrenaline. Phosphate and vanadate competed for the same binding site on the enzyme.

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Year:  1979        PMID： 486156      PMCID： PMC1161148          DOI： 10.1042/bj1810247

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  18 in total

1.  STUDIES ON LIVER ALCOHOL HYDROGENASE COMPLEXES. 3. MULTIPLE INHIBITION KINETICS IN THE PRESENCE OF TWO COMPETITIVE INHIBITORS.

Authors:  T YONETANI; H THEORELL
Journal:  Arch Biochem Biophys       Date:  1964-07-20       Impact factor: 4.013

2.  The determination of enzyme inhibitor constants.

Authors:  M DIXON
Journal:  Biochem J       Date:  1953-08       Impact factor: 3.857

3.  The presence of two (Na+ + K+)-ATPase inhibitors in equine muscle ATP: vanadate nad a dithioerythritol-dependent inhibitor.

Authors:  E E Quist; L E Hokin
Journal:  Biochim Biophys Acta       Date:  1978-08-04

4.  A convenient method for the ATPase assay.

Authors:  D LeBel; G G Poirier; A R Beaudoin
Journal:  Anal Biochem       Date:  1978-03       Impact factor: 3.365

5.  Potent inhibition of dynein adenosinetriphosphatase and of the motility of cilia and sperm flagella by vanadate.

Authors:  I R Gibbons; M P Cosson; J A Evans; B H Gibbons; B Houck; K H Martinson; W S Sale; W J Tang
Journal:  Proc Natl Acad Sci U S A       Date:  1978-05       Impact factor: 11.205

6.  Inhibition of dynein ATPase by vanadate, and its possible use as a probe for the role of dynein in cytoplasmic motility.

Authors:  T Kobayashi; T Martensen; J Nath; M Flavin
Journal:  Biochem Biophys Res Commun       Date:  1978-04-28       Impact factor: 3.575

7.  Isolation of a potent (Na-K)ATPase inhibitor from striated muscle.

Authors:  L Josephson; L C Cantley
Journal:  Biochemistry       Date:  1977-10-18       Impact factor: 3.162

8.  A characterization of vanadate interactions with the (Na,K)-ATPase. Mechanistic and regulatory implications.

Authors:  L C Cantley; L G Cantley; L Josephson
Journal:  J Biol Chem       Date:  1978-10-25       Impact factor: 5.157

9.  Commercial ATP containing traces of vanadate alters the response of (Na+ + K+) ATPase to external potassium.

Authors:  L A Beaugé; I M Glynn
Journal:  Nature       Date:  1978-04-06       Impact factor: 49.962

10.  Vanadate is a potent (Na,K)-ATPase inhibitor found in ATP derived from muscle.

Authors:  L C Cantley; L Josephson; R Warner; M Yanagisawa; C Lechene; G Guidotti
Journal:  J Biol Chem       Date:  1977-11-10       Impact factor: 5.157
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  20 in total

1.  Effects of Membrane ATPase Inhibitors on Light-Induced Phase Shifting of the Circadian Clock in Neurospora crassa.

Authors:  H Nakashima
Journal:  Plant Physiol       Date:  1982-03       Impact factor: 8.340

2.  E1BF is an essential RNA polymerase I transcription factor with an intrinsic protein kinase activity that can modulate rRNA gene transcription.

Authors:  J Zhang; H F Niu; S T Jacob
Journal:  Proc Natl Acad Sci U S A       Date:  1991-10-01       Impact factor: 11.205

3.  Novel mechanism for suppression of hyperpolarization-activated cyclic nucleotide-gated pacemaker channels by receptor-like tyrosine phosphatase-alpha.

Authors:  Jianying Huang; Aijie Huang; Qi Zhang; Yen-Chang Lin; Han-Gang Yu
Journal:  J Biol Chem       Date:  2008-09-03       Impact factor: 5.157

4.  Alkaline Phosphatase Activity of Staphylococcus aureus Grown in Biofilm and Suspension Cultures.

Authors:  Kevin M Danikowski; Tong Cheng
Journal:  Curr Microbiol       Date:  2018-05-30       Impact factor: 2.188

5.  Structurally and functionally modified forms of pp60v-src in Rous sarcoma virus-transformed cell lysates.

Authors:  M S Collett; S K Belzer; A F Purchio
Journal:  Mol Cell Biol       Date:  1984-07       Impact factor: 4.272

Review 6.  Fluoride, vanadium, nickel, arsenic, and silicon in total parenteral nutrition.

Authors:  F H Nielsen
Journal:  Bull N Y Acad Med       Date:  1984-03

7.  A unique modulator of endoplasmic reticulum stress-signalling pathways: the novel pharmacological properties of amiloride in glial cells.

Authors:  Toru Hosoi; Ayaka Kume; Kayo Otani; Tatsuya Oba; Koichiro Ozawa
Journal:  Br J Pharmacol       Date:  2009-12-15       Impact factor: 8.739

8.  A subset of signal transduction pathways is required for hippocampal growth cone collapse induced by ephrin-A5.

Authors:  Xin Yue; Cheryl Dreyfus; Tony Ah-Ng Kong; Renping Zhou
Journal:  Dev Neurobiol       Date:  2008-09-01       Impact factor: 3.964

9.  On the role of G protein activation and phosphorylation in desensitization to acetylcholine in guinea-pig atrial cells.

Authors:  W J Zang; X J Yu; H Honjo; M S Kirby; M R Boyett
Journal:  J Physiol       Date:  1993-05       Impact factor: 5.182

10.  Cadherins and synaptic plasticity: activity-dependent cyclin-dependent kinase 5 regulation of synaptic beta-catenin-cadherin interactions.

Authors:  Erin M Schuman; Sachiko Murase
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2003-04-29       Impact factor: 6.237
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