| Literature DB >> 4860485 |
Abstract
Experimental proof is given that the volume distribution spectrum of mammalian cells in suspension culture can be determined accurately with a Coulter spectrometer. Stable spectra corresponding to the predictions of a mathematical model are observed under favorable conditions of growth. Cell volume spectrometry appears to be a useful method for diagnosing the state of the culture with respect to past uniformity of growth rate and present population age distribution. In addition, it offers a method for quantitative study of the laws governing cell growth and division.Entities:
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Year: 1967 PMID: 4860485 PMCID: PMC1368065 DOI: 10.1016/S0006-3495(67)86593-7
Source DB: PubMed Journal: Biophys J ISSN: 0006-3495 Impact factor: 4.033