Literature DB >> 4858286

Reversal of morphine tolerance after medial thalamic lesions in the rat.

H Teitelbaum, G N Catravas, W L McFarland.   

Abstract

Tolerance, manifested by a diminished electroencephalographic response at cortical and subcortical recording sites, was found in rats subjected to repeated systemic injections of morphine sulfate. Reversal of tolerance to morphine resulted from destruction of the medial thalamus.

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Year:  1974        PMID: 4858286     DOI: 10.1126/science.185.4149.449

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  3 in total

1.  Effects of lesions of the ventromedial hypothalamus on naloxone-induced morphine withdrawal in rats.

Authors:  M A Linseman
Journal:  Psychopharmacologia       Date:  1976-02-02

2.  Morphine-naloxone interaction in the central cholinergic system: the influence of subcortical lesioning and electrical stimulation.

Authors:  K Jhamandas; M Sutak
Journal:  Br J Pharmacol       Date:  1976-09       Impact factor: 8.739

3.  Acute and chronic opiate effects on single units and EEG of medial thalamus and hippocampus: a latency analysis.

Authors:  M A Linseman; L A Grupp
Journal:  Psychopharmacology (Berl)       Date:  1980       Impact factor: 4.530

  3 in total

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