Literature DB >> 4854921

The isolation of cholest-5-ene-3beta,26-diol from human brain.

A G Smith, J D Gilbert, W A Harland, C J Brooks.   

Abstract

Cholest-5-ene-3beta,26-diol, isolated from human brain, was further characterized by oxidation to 3-oxocholest-4-en-26-ol and to 3-oxocholest-4-en-26-oic acid. Identification was achieved by comparison (by t.l.c., g.l.c. and g.l.c.-mass spectrometry) with corresponding reference compounds derived from kryptogenin.

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Year:  1974        PMID： 4854921      PMCID： PMC1166347          DOI： 10.1042/bj1390793

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  19 in total

1.  Mass spectrometry in structural and stereochemical problems. CXXV. Mass spectrometry of some steroid trimethylsilyl ethers.

Authors:  J Diekman; C Djerassi
Journal:  J Org Chem       Date:  1967-04       Impact factor: 4.354

2.  Antibody formation in radiation chimaeras.

Authors:  Y Zaretskaya; E I Panteleyev; L V Kovalchuk
Journal:  Folia Biol (Praha)       Date:  1968       Impact factor: 0.906

3.  Sterol metabolism. XII. 26-Hydroxycholesterol in commercial cholesterol.

Authors:  J E Van Lier; L L Smith
Journal:  Lipids       Date:  1971-02       Impact factor: 1.880

4.  Metabolism of cholest-5-ene-3 beta, 26-diol in the rat and hamster.

Authors:  N Wachtel; S Emerman; N B Javitt
Journal:  J Biol Chem       Date:  1968-10-10       Impact factor: 5.157

5.  Sterol metabolism. 9.26-hydroxycholesterol levels in the human aorta.

Authors:  L L Smith; J E Van Lier
Journal:  Atherosclerosis       Date:  1970 Jul-Aug       Impact factor: 5.162

6.  Sterol metabolism. V. A chromatographic examination of human brain sterols.

Authors:  J E van Lier; L L Smith
Journal:  Tex Rep Biol Med       Date:  1969

7.  The effects of certain C27 steroids on organ cultures of rabbit aorta.

Authors:  J D MacDougall; S Biswas; R P Cook
Journal:  Br J Exp Pathol       Date:  1965-10

8.  Squalene, 26-hydroxycholesterol and 7-ketocholesterol in human atheromatous plaques.

Authors:  C J Brooks; W A Harland; G Steel
Journal:  Biochim Biophys Acta       Date:  1966-12-07

9.  Sterol metabolism. I. 26-Hydroxycholesterol in the human aorta.

Authors:  J E Van Lier; L L Smith
Journal:  Biochemistry       Date:  1967-10       Impact factor: 3.162

10.  [Cholest-4-en-26-ol-3-one and cholesta-1,4-dien-26-ol-3-one as conponents of a new microbiologically formed type of ester].

Authors:  K Schubert; G Kaufmann; H Budzikiewicz
Journal:  Biochim Biophys Acta       Date:  1969-01-21
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  3 in total

1.  Metabolism of 27-, 25- and 24-hydroxycholesterol in rat glial cells and neurons.

Authors:  J Zhang; Y Akwa; M el-Etr; E E Baulieu; J Sjövall
Journal:  Biochem J       Date:  1997-02-15       Impact factor: 3.857

2.  Unusual urinary cholesterol metabolites following intracerebral injection of [4-14C]cholesterol into rats: I. The minor 14C-metabolite.

Authors:  R B Ramsey; H J Nicholas
Journal:  Lipids       Date:  1982-03       Impact factor: 1.880

3.  The substrate specificity and stereochemistry, reversibility and inhibition of the 3-oxo steroid delta 4-delta 5-isomerase component of cholesterol oxidase.

Authors:  A G Smith; C J Brooks
Journal:  Biochem J       Date:  1977-10-01       Impact factor: 3.857
  3 in total

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