Literature DB >> 4853118

Measurement of side effects of drugs.

E C Huskisson, J A Wojtulewski.   

Abstract

In a clinical trial of two antirheumatic agents two methods of collection of side effects were used, one with and the other without a check list of possible symptoms. Findings suggested that the use of a check list interfered with the collection of side effects. Known side effects of aspirin-tinnitus, deafness, and gastrointestinal disturbance-were more efficiently shown and symptoms not included in the check list were more likely to be reported when a check list was not used.

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Year:  1974        PMID: 4853118      PMCID: PMC1611170          DOI: 10.1136/bmj.2.5921.698

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  1 in total

1.  A sequential trial of indomethacin and sodium amylobarbitone at night in rheumatoid arthritis, with comments on the statistical method.

Authors:  M F Grayson; E C Huskisson
Journal:  Rheumatol Rehabil       Date:  1974-11
  1 in total
  12 in total

1.  Evaluation of three methods of symptom reporting in a clinical trial of felodipine.

Authors:  M A Wallander; E Dimenäs; K Svärdsudd; I Wiklund
Journal:  Eur J Clin Pharmacol       Date:  1991       Impact factor: 2.953

2.  A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents.

Authors:  R E Pemberton; L J Strand
Journal:  Dig Dis Sci       Date:  1979-01       Impact factor: 3.199

3.  The case for recording events in clinical trials.

Authors:  D C Skegg; R Doll
Journal:  Br Med J       Date:  1977-12-10

Review 4.  The way towards adverse event monitoring in clinical trials.

Authors:  M A Wallander
Journal:  Drug Saf       Date:  1993-03       Impact factor: 5.606

5.  At equipotent doses, isradipine is better tolerated than amlodipine in patients with mild-to-moderate hypertension: a double-blind, randomized, parallel-group study.

Authors:  L Hermans; A Deblander; P De Keyser; I Scheys; E Lesaffre; K J Westelinck
Journal:  Br J Clin Pharmacol       Date:  1994-10       Impact factor: 4.335

6.  Monitoring adverse reactions to antibiotics in general practice.

Authors:  C R Martys
Journal:  J Epidemiol Community Health       Date:  1982-09       Impact factor: 3.710

7.  Controlled study of atenolol in treatment of hypertension.

Authors:  L Hansson; H Aberg; B E Karlberg; A Westerlund
Journal:  Br Med J       Date:  1975-05-17

8.  Naproxen in rheumatoid arthritis. Extended trial.

Authors:  A G Mowat; B M Ansell; J M Gumpel; H F Hill; A G Hill; M Stoppard
Journal:  Ann Rheum Dis       Date:  1976-12       Impact factor: 19.103

9.  Comparison of methods to detect side-effect on clinical application of chloranolol, a beta-adrenergic receptor inhibitor.

Authors:  E Török; E Kósa; M Szontagh; P Juvancz; J Eggenhofer; J Borvendég
Journal:  Eur J Clin Pharmacol       Date:  1984       Impact factor: 2.953

10.  Long term tolerability profile of nimesulide in the treatment of osteoarthritis.

Authors:  R L Dreiser; D C Benevelli
Journal:  Drugs       Date:  1993       Impact factor: 9.546

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