Literature DB >> 4850584

Antagonism by folic acid of presynaptic inhibition in the rat cuneate nucleus.

R G Hill, A A Miller.   

Abstract

Folic acid applied topically in solution to the rat cuneate nucleus reduced presynaptic inhibition produced by peripheral stimulation. This resembles the action of picrotoxin in the same animals and it is possible that these two convulsants are acting in a similar manner by blockade of the receptors for the presynaptic inhibitory transmitter.

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Year:  1974        PMID： 4850584      PMCID： PMC1776696          DOI： 10.1111/j.1476-5381.1974.tb09619.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  5 in total

1.  Facilitatory and direct excitatory effects of folate and folinate on single neurones of cat cerebral cortex.

Authors:  J Davies; J C Watkins
Journal:  Biochem Pharmacol       Date:  1973-07-01       Impact factor: 5.858

2.  The epileptogenic action of Na-folate in the rat.

Authors:  O R Hommes; E A Obbens
Journal:  J Neurol Sci       Date:  1972-07       Impact factor: 3.181

3.  Pharmacological studies on inhibition in the cuneate nucleus of the cat.

Authors:  N R Banna; S J Jabbur
Journal:  Int J Neuropharmacol       Date:  1969-05

4.  Some studies on the convulsant action of folic acid.

Authors:  M G Baxter; A A Miller; R A Webster
Journal:  Br J Pharmacol       Date:  1973-06       Impact factor: 8.739

5.  Amino acids and presynaptic inhibition in the rat cuneate nucleus.

Authors:  N Davidson; C A Southwick
Journal:  J Physiol       Date:  1971-12       Impact factor: 5.182
  5 in total
  6 in total

Review 1.  Benefits and risks of folic acid to the nervous system.

Authors:  E H Reynolds
Journal:  J Neurol Neurosurg Psychiatry       Date:  2002-05       Impact factor: 10.154

2.  Proceedings: A study of tetramethylenedisulphotetramine (TETS) and related compounds as antagonists of presynaptic inhibition and microiontophoretically applied gamma-amino-butyric acid (GABA) and glycine in the rat cuneate nucleus.

Authors:  J F Collins; R G Hill
Journal:  Br J Pharmacol       Date:  1975-06       Impact factor: 8.739

3.  The effect of folates on the reflex activity in the isolated hemisected frog spinal cord.

Authors:  J M Loots; S Kramer; M J Brennan
Journal:  J Neural Transm       Date:  1982       Impact factor: 3.575

4.  Modulation of potassium evoked secretory function in rat cerebellar slices measured by real time monitoring: evidence of a possible role for methylfolate in cerebral tissue.

Authors:  M D Lucock; M I Levene; R Hartley
Journal:  Neurochem Res       Date:  1993-05       Impact factor: 3.996

Review 5.  Folate action in nervous system development and disease.

Authors:  Olga A Balashova; Olesya Visina; Laura N Borodinsky
Journal:  Dev Neurobiol       Date:  2018-02-06       Impact factor: 3.964

6.  Methylfolate modulates potassium evoked neuro-secretion: evidence for a role at the pteridine cofactor level of tyrosine 3-hydroxylase.

Authors:  M D Lucock; M Green; M I Levene
Journal:  Neurochem Res       Date:  1995-06       Impact factor: 3.996
  6 in total

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