Literature DB >> 4847799

Alpha-1-acetylmethadol and its N-demethylated metabolites have potent opiate action in the guinea pig isolated ileum.

R Nickander, R Booher, H Miles.   

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Year:  1974        PMID： 4847799     DOI： 10.1016/0024-3205(74)90417-2

Source DB:  PubMed          Journal:  Life Sci        ISSN： 0024-3205            Impact factor:   5.037


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  2 in total

1.  Paradoxical role of cytochrome P450 3A in the bioactivation and clinical effects of levo-alpha-acetylmethadol: importance of clinical investigations to validate in vitro drug metabolism studies.

Authors:  Evan D Kharasch; Dale Whittington; Christine Hoffer; Kevin Krudys; Keith Craig; Paolo Vicini; Pam Sheffels; Bojan Lalovic
Journal:  Clin Pharmacokinet       Date:  2005       Impact factor: 6.447

2.  Blood-brain equilibration kinetics of levo-alpha-acetyl-methadol using a chronically instrumented sheep preparation.

Authors:  David J R Foster; Mette L Jensen; Richard N Upton; Andrew A Somogyi; Cliff Grant; Allison Martinez
Journal:  Br J Pharmacol       Date:  2006-01       Impact factor: 8.739
  2 in total

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