Literature DB >> 484722

Choline chloride treatment of memory deficits in the elderly.

R C Mohs, K L Davis, J R Tinklenberg, L E Hollister, J A Yesavage, B S Kopell.   

Abstract

Eight elderly patients with mild memory impairment were given choline chloride, a drug that increases brain acetylcholine concentrations. After 16 g/day of choline for 7 days, average memory performance was not different from performance during pre- and postcholine placebo treatment, although the patient with the poorest baseline performance improved considerably on choline.

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Year:  1979        PMID: 484722     DOI: 10.1176/ajp.136.10.1275

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN: 0002-953X            Impact factor:   18.112


  3 in total

Review 1.  Critical review of clinical trials in senile dementia--II.

Authors:  J M Orgogozo; R Spiegel
Journal:  Postgrad Med J       Date:  1987-05       Impact factor: 2.401

2.  Effect of combined or separate administration of piracetam and choline on learning and memory in the rat.

Authors:  A Ennaceur; J Delacour
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

3.  EEG effects of physostigmine and choline chloride in humans.

Authors:  A Pfefferbaum; K L Davis; C L Coulter; R C Mohs; J R Tinklenberg; B S Kopell
Journal:  Psychopharmacology (Berl)       Date:  1979-04-25       Impact factor: 4.530

  3 in total

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