Literature DB >> 484554

Electrophoresis of glucocerebrosidase from normal and Gaucher disease fibroblasts.

G L Dale, J Gudas, W Woloszyn, E Beutler.   

Abstract

A polyacrylamide gel electrophoresis system for glucocerebrosidase has been developed. This method was used to characterize the glucocerebrosidase activity of normal and Gaucher disease fibroblasts; the residual glucocerebrosidase activity in adult Gaucher disease fibroblasts co-migrates with the activity from normal fibroblasts.

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Year:  1979        PMID： 484554      PMCID： PMC1685886     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  4 in total

1.  Gaucher's disease. I. Solubilization and electrophoresis of beta-glucosidase from leukocytes and cultured fibroblasts.

Authors:  F Y Choy; R G Davidson
Journal:  Pediatr Res       Date:  1978-12       Impact factor: 3.756

2.  Amino acid metabolism in mammalian cell cultures.

Authors:  H EAGLE
Journal:  Science       Date:  1959-08-21       Impact factor: 47.728

Review 3.  Gaucher's disease, a review.

Authors:  S P Peters; R E Lee; R H Glew
Journal:  Medicine (Baltimore)       Date:  1977-09       Impact factor: 1.889

4.  Enzyme replacement therapy in Gaucher's disease: a rapid, high-yield method for purification of glucocerebrosidase.

Authors:  G L Dale; E Beutler
Journal:  Proc Natl Acad Sci U S A       Date:  1976-12       Impact factor: 11.205
  4 in total

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