Literature DB >> 4834369

Platelet and plasma fibrinogens are identical gene products.

R F Doolittle, T Takagi, B A Cottrell.   

Abstract

Human platelet fibrinogen has been shown to be indistinguishable from plasma fibrinogen by a variety of criteria, including subunit composition and cross-linking characteristics as judged by sodium dodecyl sulfate-gel electro phoresis, quantitative amino terminal analysis of fibrin, and the amino acid compositions of fibrinopeptides released from platelet and plasma fibrinogens is products of the same gene or genes.

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Year:  1974        PMID: 4834369     DOI: 10.1126/science.185.4148.368

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  4 in total

1.  Inhibition of human platelet aggregation by monovalent antifibrinogen antibody fragments.

Authors:  D M Tollefsen; P W Majerus
Journal:  J Clin Invest       Date:  1975-06       Impact factor: 14.808

2.  Platelet alpha-granule fibrinogen, albumin, and immunoglobulin G are not synthesized by rat and mouse megakaryocytes.

Authors:  P Handagama; D A Rappolee; Z Werb; J Levin; D F Bainton
Journal:  J Clin Invest       Date:  1990-10       Impact factor: 14.808

3.  Incorporation of intravenously injected albumin, immunoglobulin G, and fibrinogen in guinea pig megakaryocyte granules.

Authors:  P J Handagama; M A Shuman; D F Bainton
Journal:  J Clin Invest       Date:  1989-07       Impact factor: 14.808

4.  Fibrinogen Manchester. Detection of a heterozygous phenotype in the intraplatelet pool.

Authors:  C Southan; D A Lane; I Knight; H Ireland; J Bottomley
Journal:  Biochem J       Date:  1985-08-01       Impact factor: 3.857

  4 in total

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