Literature DB >> 483358

Specific destruction of human endothelial cell monolayers by anti-DRw antisera.

H Hirschberg, T Moen, E Throsby.   

Abstract

Human endothelial cells were separated by collagenase digestion from the umbilical vein of newborns. The cytotoxic effect of antisera against HLA-DRw antigens was tested on monolayers of endothelial cells, using a 51Cr retention microcytotoxicity assay in the presence of rabbit complement. Of the endothelial monolayers tested, significant concordance between the typing results obtained using cord blood-derived B lymphocytes and endothelial cell monolayers was observed. A rabbit anti-human polyspecific B cell antiserum was also capable of completely lysing the endothelial monolayers tested. In addition, 51Cr-labelled dissociated endothelial cells were lysed by nonimmune peripheral blood mononuclear cells in the presence of DRw antisera having a specificity for the target endothelium.

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Year:  1979        PMID： 483358     DOI： 10.1097/00007890-197908000-00009

Source DB:  PubMed          Journal:  Transplantation        ISSN： 0041-1337            Impact factor:   4.939


  17 in total

1.  The effect of gamma-interferon on HLA class II antigen expression on isolated human nasal chondrocytes.

Authors:  J Bujia; E Wilmes; F Krombach; C Hammer; E Kastenbauer
Journal:  Eur Arch Otorhinolaryngol       Date:  1990       Impact factor: 2.503

2.  AIDS-related Kaposi's sarcoma displays differential expression of endothelial surface antigens.

Authors:  P A Scully; H K Steinman; C Kennedy; K Trueblood; D M Frisman; J R Voland
Journal:  Am J Pathol       Date:  1988-02       Impact factor: 4.307

3.  Phenotypic heterogeneity of vascular endothelial cells in the human kidney.

Authors:  T Kinjo; M Takashi; K Miyake; H Nagura
Journal:  Cell Tissue Res       Date:  1989-04       Impact factor: 5.249

Review 4.  The aetiology and pathogenesis of major systemic vasculitides.

Authors:  C O Savage; Y C Ng
Journal:  Postgrad Med J       Date:  1986-07       Impact factor: 2.401

Review 5.  The endothelium--astrocyte immune control system of the brain.

Authors:  A Fontana; W Fierz
Journal:  Springer Semin Immunopathol       Date:  1985

6.  The expression of endothelial cell surface antigens by AIDS-associated Kaposi's sarcoma. Evidence for a vascular endothelial cell origin.

Authors:  J L Rutgers; R Wieczorek; F Bonetti; K L Kaplan; D N Posnett; A E Friedman-Kien; D M Knowles
Journal:  Am J Pathol       Date:  1986-03       Impact factor: 4.307

7.  MHC antigen expression in sequential biopsies from cardiac transplant patients--correlation with rejection.

Authors:  A Suitters; M Rose; A Higgins; M H Yacoub
Journal:  Clin Exp Immunol       Date:  1987-09       Impact factor: 4.330

8.  Intrathyroidal HLA-DR expression and T lymphocyte phenotypes in Graves' thyrotoxicosis, Hashimoto's thyroiditis and nodular colloid goitre.

Authors:  R Jansson; A Karlsson; U Forsum
Journal:  Clin Exp Immunol       Date:  1984-11       Impact factor: 4.330

9.  Human endothelial cell-lymphocyte interaction. Endothelial cells function as accessory cells necessary for mitogen-induced human T lymphocyte activation in vitro.

Authors:  E R Ashida; A R Johnson; P E Lipsky
Journal:  J Clin Invest       Date:  1981-05       Impact factor: 14.808

10.  Eluted rheumatoid synovial tissue T cell subsets and HLA-DR bearing cells at different stages of fractionation.

Authors:  T Egeland; O Førre
Journal:  Clin Rheumatol       Date:  1983-03       Impact factor: 2.980
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