Literature DB >> 4832759

A simple and inexpensive membrane "lung" for small organ perfusion.

R L Hamilton, M N Berry, M C Williams, E M Severinghaus.   

Abstract

A disposable coil of thin-walled Silastic tubing, permeable to oxygen and carbon dioxide, functioned as a "lung" for perfusion of isolated rat liver. This "lung," which can be easily assembled from laboratory supplies, has a number of advantages over devices that utilize large air-liquid interfaces for gas exchange. Rates of hepatic lipoprotein triglyceride secretion, comparable to those obtained with more complex oxygenation systems, are achieved with this simple device.

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Year:  1974        PMID: 4832759

Source DB:  PubMed          Journal:  J Lipid Res        ISSN: 0022-2275            Impact factor:   5.922


  43 in total

1.  An improved technique for isolated perfusion of rat livers and an evaluation of perfusates.

Authors:  H J Mischinger; T R Walsh; T Liu; P N Rao; R Rubin; K Nakamura; S Todo; T E Starzl
Journal:  J Surg Res       Date:  1992-08       Impact factor: 2.192

2.  A distinct nitric oxide and adenosine A1 receptor dependent hepatic artery vasodilatatory response in the CCl-cirrhotic liver.

Authors:  Alexander Zipprich; Wajahat Z Mehal; Cristina Ripoll; Roberto J Groszmann
Journal:  Liver Int       Date:  2010-05-24       Impact factor: 5.828

3.  Chylomicron remnant and asialoglycoprotein metabolism are independent.

Authors:  A D Cooper; D Coleman
Journal:  Lipids       Date:  1985-10       Impact factor: 1.880

4.  A modified apparatus for dual, sterilized, isolated perfusion of the rat liver.

Authors:  T Liu; T R Walsh; H Mischinger; P N Rao; P Chelvakumar; R Rubin; T E Starzl
Journal:  J Invest Surg       Date:  1990       Impact factor: 2.533

5.  The regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in the isolated perfused rat liver.

Authors:  A D Cooper
Journal:  J Clin Invest       Date:  1976-06       Impact factor: 14.808

6.  Digitonin-collagenase perfusion for efficient separation of periportal or perivenous hepatocytes.

Authors:  K O Lindros; K E Penttilä
Journal:  Biochem J       Date:  1985-06-15       Impact factor: 3.857

7.  Improved hepatic function in the 24-hour preserved rat liver with UW-lactobionate solution and SRI 63-441.

Authors:  S J Ontell; L Makowka; P Ove; T E Starzl
Journal:  Gastroenterology       Date:  1988-12       Impact factor: 22.682

8.  Efficient clearance of non-transferrin-bound iron by rat liver. Implications for hepatic iron loading in iron overload states.

Authors:  P Brissot; T L Wright; W L Ma; R A Weisiger
Journal:  J Clin Invest       Date:  1985-10       Impact factor: 14.808

9.  Inhibition of glucose uptake and glycogenolysis by availability of oleate in well-oxygenated perfused skeletal muscle.

Authors:  M J Rennie; J O Holloszy
Journal:  Biochem J       Date:  1977-11-15       Impact factor: 3.857

10.  Studies on the production of low density lipoproteins by perfused livers from nonhuman primates. Effect of dietary cholesterol.

Authors:  F L Johnson; R W St Clair; L L Rudel
Journal:  J Clin Invest       Date:  1983-07       Impact factor: 14.808

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