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Literature DB >> 4825980

Production of a potent vaccine from the attenuated M-44 strain of Coxiella burneti.

Abstract

The attenuated M-44 strain of Coxiella burneti was heated to free it of adventitious agents that may have been present. Parallel titrations of the strain before and after heating indicated that the virulence for guinea pigs was markedly decreased. Guinea pigs immunized with the strain derived after heat treatment were protected from the effects of challenge with C. burneti in either phase I or II.

Entities: Disease Species

Mesh：

Substances：

Year: 1974 PMID： 4825980 PMCID： PMC380134 DOI： 10.1128/am.27.4.777-783.1974

Source DB: PubMed Journal: Appl Microbiol ISSN： 0003-6919

13 in total

1. STAINING RICKETTSIAE IN YOLK-SAC CULTURES.

Authors: D F GIMENEZ
Journal: Stain Technol Date: 1964-05

2. REPORT OF A FIELD STUDY WITH Q FEVER VACCINE.

Authors: S VIVONA; J P LOWENTHAL; S BERMAN; A S BENENSON; J E SMADEL
Journal: Am J Hyg Date: 1964-03

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Authors: P F ZDRODOVSKII; V A GENIG
Journal: Vopr Virusol Date: 1962 May-Jun

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Authors: V A GENIG
Journal: Vestn Akad Med Nauk SSSR Date: 1960

5. Safety test for Q fever vaccine.

Authors: S BERMAN; G COLE; J P LOWENTHAL; R B GOCHENOUR
Journal: J Bacteriol Date: 1960-05 Impact factor: 3.490

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Authors: S Berman; R B Gochenour; G Cole; J P Lowenthal; A S Benenson
Journal: J Bacteriol Date: 1961-05 Impact factor: 3.490

7. A method of purifying Coxiella burnetii and other pathogenic Rickettsiae.

Authors: R A ORMSBEE
Journal: J Immunol Date: 1962-01 Impact factor: 5.422

8. Immunization against scrub typhus. II. Preparation of lyophilized living vaccine.

Authors: E B JACKSON; J E SMADEL
Journal: Am J Hyg Date: 1951-05

9. Preparation of highly purified concentrates of Coxiella burneti.

Authors: D S Spicer; A N DeSanctis; J M Beiler
Journal: Proc Soc Exp Biol Med Date: 1970-12

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Authors: V A Genig; E N Kniazeva; P S Tsel'nikov; M M Miroshnichenko
Journal: Vopr Virusol Date: 1965 May-Jun

3 in total