Literature DB >> 4825238

Proteolysis of myosin during platelet storage.

J Abramowitz, A Stracher, T C Detwiler.   

Abstract

Physical properties of actomyosin from either fresh or stored platelets have been compared. Actomyosin obtained from platelets after 3 days of storage contained myosin that was 60-80% degraded to myosin rod. No myosin rod was detected in fresh platelets. The platelet myosin rod is similar to the rod produced by limited proteolysis of skeletal muscle myosin.

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Year:  1974        PMID: 4825238      PMCID: PMC302638          DOI: 10.1172/JCI107698

Source DB:  PubMed          Journal:  J Clin Invest        ISSN: 0021-9738            Impact factor:   14.808


  5 in total

Review 1.  Thrombosthenin, the contractile protein from blood platelets and its relation to other contractile proteins.

Authors:  M Bettex-Galland; E F Lüscher
Journal:  Adv Protein Chem       Date:  1965

2.  Isolation and characterization of myosin and two myosin fragments from human blood platelets.

Authors:  R S Adelstein; T D Pollard; W M Kuehl
Journal:  Proc Natl Acad Sci U S A       Date:  1971-11       Impact factor: 11.205

Review 3.  Structure and function of the myofibrillar contractile proteins.

Authors:  P Dreizen
Journal:  Annu Rev Med       Date:  1971       Impact factor: 13.739

4.  Substructure of the myosin molecule. I. Subfragments of myosin by enzymic degradation.

Authors:  S Lowey; H S Slayter; A G Weeds; H Baker
Journal:  J Mol Biol       Date:  1969-05-28       Impact factor: 5.469

5.  The differential effect of Ca-ATP and Mg-ATP on platelet actomyosin.

Authors:  J Abramowitz; A Stracher; T Detwiler
Journal:  Biochem Biophys Res Commun       Date:  1972-11-15       Impact factor: 3.575

  5 in total
  2 in total

1.  Interactions of actin, myosin, and an actin-binding protein of chronic myelogenous leukemia leukocytes.

Authors:  L A Boxer; T P Stossel
Journal:  J Clin Invest       Date:  1976-04       Impact factor: 14.808

2.  Human platelet myosin. II. In vitro assembly and structure of myosin filaments.

Authors:  R Niederman; T D Pollard
Journal:  J Cell Biol       Date:  1975-10       Impact factor: 10.539

  2 in total

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