Literature DB >> 4824216

The reaction of diethyl pyrocarbonate with pyruvate kinase.

L G Dann, H G Britton.   

Abstract

Diethyl pyrocarbonate inactivates muscle pyruvate kinase with the substitution of 3-4 histidine residues per subunit. Phosphoenolpyruvate, ATP and ADP to a lesser extent, and Mg(2+) and pyruvate to a small extent, protect against inactivation.

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Year:  1974        PMID： 4824216      PMCID： PMC1166129          DOI： 10.1042/bj1370405

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  12 in total

1.  KINETIC AND MAGNETIC RESONANCE STUDIES OF THE PYRUVATE KINASE REACTION. I. DIVALENT METAL COMPLEXES OF PYRUVATE KINASE.

Authors:  A S MILDVAN; M COHN
Journal:  J Biol Chem       Date:  1965-01       Impact factor: 5.157

2.  Bicarbonate- and hydroxylamine-dependent degradation of adenosine triphosphate.

Authors:  F P KUPIECKI; M J COON
Journal:  J Biol Chem       Date:  1959-09       Impact factor: 5.157

3.  The active site and mechanism of action of bovine pancreatic ribonuclease. 7. The catalytic mechanism.

Authors:  D Findlay; D G Herries; A P Mathias; B R Rabin; C A Ross
Journal:  Biochem J       Date:  1962-10       Impact factor: 3.857

4.  Inhibition of muscle pyruvate kinase by creatine phosphate.

Authors:  R G Kemp
Journal:  J Biol Chem       Date:  1973-06-10       Impact factor: 5.157

5.  Role of lysyl epsilon-amino groups in adenosine diphosphate binding and catalytic activity of pyruvate kinase.

Authors:  P F Hollenberg; M Flashner; M J Coon
Journal:  J Biol Chem       Date:  1971-02-25       Impact factor: 5.157

6.  Subunit structure of rabbit muscle pyruvate kinase.

Authors:  G L Cottam; P F Hollenberg; M J Coon
Journal:  J Biol Chem       Date:  1969-03-25       Impact factor: 5.157

7.  [The active site of ATP: guanidine phosphotransferases. II. Evidence for an essential histidine residue through use of diethylpyrocarbonate].

Authors:  L A Pradel; R Kassab
Journal:  Biochim Biophys Acta       Date:  1968-10-08

8.  Evidence for the presence of two types of pyruvate kinase in rat liver.

Authors:  T Tanaka; Y Harano; H Morimura; R Mori
Journal:  Biochem Biophys Res Commun       Date:  1965-10-08       Impact factor: 3.575

9.  Ionic properties of an essential histidine residue in pig heart lactate dehydrogenase.

Authors:  J J Holbrook; V A Ingram
Journal:  Biochem J       Date:  1973-04       Impact factor: 3.857

10.  Regulation of rat liver pyruvate kinase. The effect of preincubation, pH, copper ions, fructose 1,6-diphosphate and dietary changes on enzyme activity.

Authors:  E Bailey; F Stirpe; C B Taylor
Journal:  Biochem J       Date:  1968-07       Impact factor: 3.857
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  4 in total

1.  The regulatory properties of rabbit muscle pyruvate kinase. The effect of pH.

Authors:  R B Gregory; S Ainsworth
Journal:  Biochem J       Date:  1981-06-01       Impact factor: 3.857

2.  Modification of lactate oxidase with diethyl pyrocarbonate. Evidence for an active-site histidine residue.

Authors:  C Y Soon; M G Shepherd; P A Sullivan
Journal:  Biochem J       Date:  1977-08-01       Impact factor: 3.857

3.  Chemical modification of Pseudomonas fluorescens malonyl-CoA synthetase by diethylpyrocarbonate: kinetic evidence for an essential histidyl residue on alpha subunit.

Authors:  Y S Kim; Y I Kim; S K Bang
Journal:  J Protein Chem       Date:  1991-08

4.  Kinetics and mechanism of action of muscle pyruvate kinase.

Authors:  L G Dann; H G Britton
Journal:  Biochem J       Date:  1978-01-01       Impact factor: 3.857
  4 in total

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