| Literature DB >> 4822472 |
Abstract
Mathematical formulae for the sampling variances of average heterozygosity and Nei's genetic distance are developed. These sampling variances are decomposed into their two components, i.e. the inter-locus and intra-locus variances. The relationship between the number of loci and the number of individuals per locus to be examined for estimating average heterozygosity and genetic distance is also discussed. The utility of the inter-locus variance of heterozygosity for studying the mechanism of maintenance of genetic variability in populations is indicated.Mesh:
Year: 1974 PMID: 4822472 PMCID: PMC1213072
Source DB: PubMed Journal: Genetics ISSN: 0016-6731 Impact factor: 4.562