Literature DB >> 4820639

Trypsin and chymotrypsin in duodenal aspirate and faeces in response to secretin and cholecystokinin-pancreozymin.

J K Sale, D M Goldberg, B Thjodleifsson, K G Wormsley.   

Abstract

The secretion of trypsin and chymotrypsin into the duodenum in response to secretin and CCK-PZ has been compared with the faecal excretion of the enzymes following similar stimulation in 47 individuals undergoing clinical investigation. The faecal output of chymotrypsin correlated well, but trypsin less satisfactorily, with the secretion of the respective enzymes into the duodenum. The faecal excretion of chymotrypsin following stimulation with secretin and CCK-PZ can therefore be used as an index of pancreatic enzyme-secretory capacity.

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Year:  1974        PMID： 4820639      PMCID： PMC1412895          DOI： 10.1136/gut.15.2.132

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  24 in total

1.  Stimulation of pancreatic secretion by intraduodenal infusion of bile-salts.

Authors:  K G Wormsley
Journal:  Lancet       Date:  1970-09-19       Impact factor: 79.321

2.  The response to infusion of a combination of secretin and pancreozymin in health and disease.

Authors:  K G Wormsley
Journal:  Scand J Gastroenterol       Date:  1969       Impact factor: 2.423

3.  Diagnostic value of fecal chymotrypsin and trypsin assessment for detection of pancreatic disease. A comparative study.

Authors:  R W Ammann; E Tagwecher; H Kashiwagi; H Rosenmund
Journal:  Am J Dig Dis       Date:  1968-02

4.  The measurement of faecal chymotrypsin: a screening test for pancreatic exocrine insufficiency.

Authors:  L Muller; Z S Wisniewski; J Hansky
Journal:  Australas Ann Med       Date:  1970-02

5.  Fate of trypsin and chymotrypsin in the human small intestine.

Authors:  D M Goldberg; R Campbell; A D Roy
Journal:  Gut       Date:  1969-06       Impact factor: 23.059

6.  Fecal enzyme assay as an aid to the diagnosis of pancreatic exocrine insufficiency.

Authors:  P Wilding; J G Banwell; W T Cooke
Journal:  Am J Dig Dis       Date:  1966-09

7.  Secretory response of the human pancreas to continuous intravenous infusion of pancreozymin-cholecystokinin (Cecekin).

Authors:  J G Banwell; B E Northam; W T Cooke
Journal:  Gut       Date:  1967-08       Impact factor: 23.059

8.  pH and pancreatic enzymes in the human duodenum during digestion of a standard meal.

Authors:  H Worning; S Müllertz
Journal:  Scand J Gastroenterol       Date:  1966       Impact factor: 2.423

9.  [Bile flow and pancreas secretion].

Authors:  M M Forell; H Stahlheber
Journal:  Klin Wochenschr       Date:  1966-10-15

10.  The interrelationships of pancreatic enzymes in human duodenal aspirate.

Authors:  D M Goldberg; K G Wormsley
Journal:  Gut       Date:  1970-10       Impact factor: 23.059
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  10 in total

1.  Limitations of faecal chymotrypsin as a screening test for chronic pancreatitis.

Authors:  L Riedel; A R Walker; I Segal; A E Mohamed; A E Smyth; B Daya; I Naik
Journal:  Gut       Date:  1991-03       Impact factor: 23.059

2.  A new faecal chymotrypsin method for evaluating the exocrine pancreatic function in patients with different pancreatic diseases.

Authors:  C Lesi; G V Melzi D'Eril; M S Scotta; L Zoni; P Malaguti
Journal:  Int J Pancreatol       Date:  1988-03

Review 3.  Pancreatic extracts in the treatment of pancreatic exocrine insufficiency.

Authors:  J H Saunders; K G Wormsley
Journal:  Gut       Date:  1975-02       Impact factor: 23.059

4.  Faecal chymotrypsin: a reliable index of exocrine pancreatic function.

Authors:  G A Brown; D Sule; J Williams; J W Puntis; I W Booth; A S McNeish
Journal:  Arch Dis Child       Date:  1988-07       Impact factor: 3.791

5.  Faecal chymotrypsin concentrations in neonates with cystic fibrosis and healthy controls.

Authors:  G A Brown; R B Halliday; P J Turner; C A Smalley
Journal:  Arch Dis Child       Date:  1988-10       Impact factor: 3.791

Review 6.  Laboratory tests in the diagnosis of the chronic pancreatic diseases. Part 5. Stool enzyme measurements.

Authors:  E J Boyd; K G Wormsley
Journal:  Int J Pancreatol       Date:  1988-03

Review 7.  Exocrine pancreatic function tests.

Authors:  P G Lankisch
Journal:  Gut       Date:  1982-09       Impact factor: 23.059

8.  [Studies on the value of fecal tryptic and chymotryptic activity in the diagnosis and therapy of cystic fibrosis (author's transl)].

Authors:  J Weise; Y Kobayashi; W Tolckmitt
Journal:  Eur J Pediatr       Date:  1976-05-04       Impact factor: 3.183

9.  Effect of intraduodenal magnesium sulphate on pancreas and gallbladder of man.

Authors:  J H Saunders; B Thjodleifsson; K G Wormsley
Journal:  Gut       Date:  1976-06       Impact factor: 23.059

10.  Exocrine Dysfunction Correlates with Endocrinal Impairment of Pancreas in Type 2 Diabetes Mellitus.

Authors:  H R Prasanna Kumar; H Basavana Gowdappa; Tejashwi Hosmani; Tejashri Urs
Journal:  Indian J Endocrinol Metab       Date:  2018 Jan-Feb
  10 in total

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