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Literature DB >> 4820628

Leucocyte migration studies in Crohn's disease using Crohn's colon homogenate and mitochondrial and microsomal fractions.

E R Richens, M J Williams, K R Gough, R J Ancill.

Abstract

Leucocytes from 38 patients with Crohn's disease were tested for evidence of migration inhibition in the presence of preparations of colon from a patient with this disease. The occurrence of migration inhibition showed a positive correlation with clinically active disease and a negative correlation with immunosuppressive treatment. It was not seen with leucocytes from 12 healthy subjects.

Entities: Disease Species

Mesh：

Year: 1974 PMID： 4820628 PMCID： PMC1412945 DOI： 10.1136/gut.15.1.19

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

17 in total

Review 1. A leucocyte migration technique for in vitro detection of cellular (delayed type) hypersensitivity in man.

Authors: G Bendixen; M Soborg
Journal: Dan Med Bull Date: 1969-01

2. Cellular hypersensitivity in Hashimoto's thyroiditis. Specific action of thyroid extract upon the migration of leucocytes in vitro.

Authors: M Soborg; P Halberg
Journal: Acta Med Scand Date: 1968 Jan-Feb

3. Inflammatory bowel disease. The role of lymphotoxin in the cytotoxicity of lymphocytes for colonic epithelial cells.

Authors: R G Shorter; K A Huizenga; R J Spencer; S K Guy
Journal: Am J Dig Dis Date: 1972-08

4. Leucocyte migration inhibition with Kveim antigen in Crohn's disease.

Authors: J Brostoff; J G Walker
Journal: Clin Exp Immunol Date: 1971-12 Impact factor: 4.330

5. Anti-adrenal, cellular hypersensitivity in Addison's disease.

Authors: J Nerup; V Andersen; G Bendixen
Journal: Clin Exp Immunol Date: 1969-04 Impact factor: 4.330

6. Investigation of the pathogenic mechanisms in regional enteritis with in vitro lymphocyte cultures.

Authors: K Parent; J Barrett; I D Wilson
Journal: Gastroenterology Date: 1971-10 Impact factor: 22.682

7. Migration inhibition studies in human disease.

Authors: J Brostoff
Journal: Proc R Soc Med Date: 1970-09

8. In-vitro inhibition of leucocyte migration in Crohn's disease by a sarcoid spleen suspension.

Authors: J M Willoughby; D N Mitchell
Journal: Br Med J Date: 1971-07-17

9. Cellular hypersensitivity to components of intestinal mucosa in ulcerative colitis and Crohn's disease.

Authors: G Bendixen
Journal: Gut Date: 1969-08 Impact factor: 23.059

10. In vitro detection of cellular hypersensitivity in man. Specific migration inhibition of white blood cells from brucella-positive persons.

Authors: M Soborg
Journal: Acta Med Scand Date: 1967-08

8 in total

1. The distribution of mucosal antibodies in the bowel of patients with Crohn's disease.

Authors: F H Green; H Fox
Journal: Gut Date: 1975-02 Impact factor: 23.059

2. Comparative mapping of the local distribution of immunoglobulin-containing cells in ulcerative colitis and Crohn's disease of the colon.

Authors: K Baklien; P Brandtzaeg
Journal: Clin Exp Immunol Date: 1975-11 Impact factor: 4.330

3. Leukocyte migration test in Crohn's disease, ulcerative colitis, and ankylosing spondylitis using Crohn's colon homogenate, mitochondrial, and microsomal fractions.

Authors: M J Williams; E R Richens; K R Gough; R J Ancill
Journal: Am J Dig Dis Date: 1975-05