Literature DB >> 4815723

Parathyroid secretion: discovery of a major calcium-dependent protein.

B Kemper, J F Habener, A Rich, J T Potts.   

Abstract

Bovine parathyroid tissue incubated in vitro secretes a protein that is distinct from both parathyroid hormone and proparathyroid hormone and comprises about 50 percent of the total secreted protein. This protein appears to be an aggregate consisting of two or more subunits of molecular weight 70,000 as determined by polyacrylamide gel electrophoresis in sodium dodecyl sulfate. Although the function of this protein is unknown, the secretion rates of both the protein and parathyroid hormone respond in parallel to changes in the concentration of calcium in the medium.

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Year:  1974        PMID： 4815723     DOI： 10.1126/science.184.4133.167

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  13 in total

1.  A quantitative ultrastructural study of microtubule content and secretory granule accumulation in parathyroid glands of phosphate- and colchicine-treated rats.

Authors:  E P Reaven; G M Reaven
Journal:  J Clin Invest       Date:  1975-07       Impact factor: 14.808

Review 2.  Phosphate sensing.

Authors:  Clemens Bergwitz; Harald Jüppner
Journal:  Adv Chronic Kidney Dis       Date:  2011-03       Impact factor: 3.620

3.  C cell (parafollicular cell) -- immunoreactive thyroglobulin: purification, identification and immunological characterization.

Authors:  Y Kameda; A Ikeda
Journal:  Histochemistry       Date:  1979-04-03

4.  Similarity of secretory protein I from parathyroid gland to chromogranin A from adrenal medulla.

Authors:  D V Cohn; R Zangerle; R Fischer-Colbrie; L L Chu; J J Elting; J W Hamilton; H Winkler
Journal:  Proc Natl Acad Sci U S A       Date:  1982-10       Impact factor: 11.205

5.  Synthesis, intracellular distribution, and secretion of multiple forms of parathyroid secretory protein-I.

Authors:  J J Morrissey; R E Shofstall; J W Hamilton; D V Cohn
Journal:  Proc Natl Acad Sci U S A       Date:  1980-11       Impact factor: 11.205

6.  Phosphorylation of parathyroid secretory protein.

Authors:  G Bhargava; J Russell; L M Sherwood
Journal:  Proc Natl Acad Sci U S A       Date:  1983-02       Impact factor: 11.205

Review 7.  Regulation of phosphate homeostasis by PTH, vitamin D, and FGF23.

Authors:  Clemens Bergwitz; Harald Jüppner
Journal:  Annu Rev Med       Date:  2010       Impact factor: 13.739

8.  Quantitative Secretomic Analysis Identifies Extracellular Protein Factors That Modulate the Metastatic Phenotype of Non-Small Cell Lung Cancer.

Authors:  Rongkuan Hu; Kenneth E Huffman; Michael Chu; Yajie Zhang; John D Minna; Yonghao Yu
Journal:  J Proteome Res       Date:  2016-01-25       Impact factor: 4.466

9.  Responsiveness of neoplastic and hyperplastic parathyroid tissues to calcium in vitro.

Authors:  J F Habener
Journal:  J Clin Invest       Date:  1978-08       Impact factor: 14.808

10.  Interrelated role of Klotho and calcium-sensing receptor in parathyroid hormone synthesis and parathyroid hyperplasia.

Authors:  Yi Fan; Weiqing Liu; Ruiye Bi; Michael J Densmore; Tadatoshi Sato; Michael Mannstadt; Quan Yuan; Xuedong Zhou; Hannes Olauson; Tobias E Larsson; Hakan R Toka; Martin R Pollak; Edward M Brown; Beate Lanske
Journal:  Proc Natl Acad Sci U S A       Date:  2018-04-04       Impact factor: 11.205
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