Literature DB >> 48126

Etomidate, a new water-soluble non-barbiturate intravenous induction agent.

M Morgan, J Lumley, J G Whitwam.   

Abstract

This paper describes clinical experimence, in 100 patients, with the new non-barbiturate, water soluble induction agent, etomidate. This drug produces sleep in one arm/brain circulation-time. There was no effect on pulse-rate, a slight fall in blood-pressure, and a low frequency of apnoea. Involuntary movements were noted, and in some patients these were severe. Etomidate warrants further evaluation as an intravenous induction agent.

Entities:  

Mesh:

Substances:

Year:  1975        PMID: 48126     DOI: 10.1016/s0140-6736(75)92011-5

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  17 in total

1.  An evaluation of combining thiopentone and etomidate for the induction of anaesthesia.

Authors:  R M Slater; B J Pollard; T M Young; L P Hunt
Journal:  Postgrad Med J       Date:  1990-07       Impact factor: 2.401

2.  [Etomidate: cardiovascular effects of a new intravenous anesthetic agent].

Authors:  K Rifat; Z Gamulin; M Gemperle
Journal:  Can Anaesth Soc J       Date:  1976-09

Review 3.  Clinical and molecular pharmacology of etomidate.

Authors:  Stuart A Forman
Journal:  Anesthesiology       Date:  2011-03       Impact factor: 7.892

4.  Pharmacokinetics of intravenous anaesthetics: implications for clinical use.

Authors:  M M Ghoneim; K Korttila
Journal:  Clin Pharmacokinet       Date:  1977 Sep-Oct       Impact factor: 6.447

Review 5.  Identification and characterization of anesthetic targets by mouse molecular genetics approaches.

Authors:  Berthold Drexler; Bernd Antkowiak; Elif Engin; Uwe Rudolph
Journal:  Can J Anaesth       Date:  2010-12-21       Impact factor: 5.063

6.  Analogues of etomidate: modifications around etomidate's chiral carbon and the impact on in vitro and in vivo pharmacology.

Authors:  Ervin Pejo; Peter Santer; Spencer Jeffrey; Hilary Gallin; S Shaukat Husain; Douglas E Raines
Journal:  Anesthesiology       Date:  2014-08       Impact factor: 7.892

7.  Effects of althesin, etomidate and fentanyl on haemodynamics and myocardial oxygen consumption in man.

Authors:  D Patschke; J B Brückner; H J Eberlein; W Hess; J Tarnow; A Weymar
Journal:  Can Anaesth Soc J       Date:  1977-01

Review 8.  Adverse effects of general anaesthetics.

Authors:  M C Berthoud; C S Reilly
Journal:  Drug Saf       Date:  1992 Nov-Dec       Impact factor: 5.606

9.  Further experience with etomidate.

Authors:  C E Famewo; C O Odugbesan
Journal:  Can Anaesth Soc J       Date:  1978-03

10.  Anesthetic drug development: Novel drugs and new approaches.

Authors:  Hovig V Chitilian; Roderic G Eckenhoff; Douglas E Raines
Journal:  Surg Neurol Int       Date:  2013-03-19
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.