Literature DB >> 4808859

DNA synthesis and mitosis in well-differentiated mammalian cardiocytes.

M A Goldstein, W C Claycomb, A Schwartz.   

Abstract

Incorporation of [(3)H]thymidine into nuclei of heart cells of 2-day-old rats indicates that neonatal cardiac cells containing well-aligned myofibrils synthesize DNA. In these highly differentiated cells, neither the presence of contractile proteins nor their organization into myofibrils inhibits either DNA synthesis or mitosis.

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Year:  1974        PMID: 4808859     DOI: 10.1126/science.183.4121.212

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  2 in total

1.  Induction of DNA synthesis and apoptosis in cardiac myocytes by E1A oncoprotein.

Authors:  Y Liu; R N Kitsis
Journal:  J Cell Biol       Date:  1996-04       Impact factor: 10.539

2.  Wnt/β-catenin signaling in heart regeneration.

Authors:  Gunes Ozhan; Gilbert Weidinger
Journal:  Cell Regen (Lond)       Date:  2015-07-08
  2 in total

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