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Literature DB >> 480471

Mutagenic specificity in reovirus.

Abstract

Mutagenic specificity in response to chemical mutagens has been observed with certain temperature-sensitive mutants of reovirus type 3. One mutant induced by nitrous acid reverted specifically with nitrous acid. Three nitrosoguanidine-induced mutants reverted after nitrous acid treatment. These findings thus suggest that analysis of chemical induction of reversion from the temperature-sensitive phenotype may be a useful approach for studying the nature of mutation in animal viruses.

Entities: Chemical Species

Mesh：

Substances：

Year: 1979 PMID： 480471 PMCID： PMC353402

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

13 in total

1. IDENTIFICATION OF THE ALTERED BASES IN MUTATED SINGLE-STRANDED DNA. I. IN VITRO MUTAGENESIS BY HYDROXYLAMINE, ETHYL METHANESULFONATE AND NITROUS ACID.

Authors: I TESSMAN; R K PODDAR; S KUMAR
Journal: J Mol Biol Date: 1964-08 Impact factor: 5.469

2. Reversal of mutant phenotypes by 5-fluorouracil: an approach to nucleotide sequences in messenger-RNA.

Authors: S P CHAMPE; S BENZER
Journal: Proc Natl Acad Sci U S A Date: 1962-04-15 Impact factor: 11.205

3. Production of mutants of tobacco mosaic virus by chemical alteration of its ribonucleic acid in vitro.

Authors: A GIERER; K W MUNDRY
Journal: Nature Date: 1958-11-22 Impact factor: 49.962

4. THE DIFFERENCE BETWEEN SPONTANEOUS AND BASE-ANALOGUE INDUCED MUTATIONS OF PHAGE T4.

Authors: E Freese
Journal: Proc Natl Acad Sci U S A Date: 1959-04 Impact factor: 11.205

5. Local mutagenesis: a method for generating viral mutants with base substitutions in preselected regions of the viral genome.

Authors: D Shortle; D Nathans
Journal: Proc Natl Acad Sci U S A Date: 1978-05 Impact factor: 11.205

1. Molecular biology of rotaviruses. III. Isolation and characterization of temperature-sensitive mutants of bovine rotavirus.

Authors: G P Faulkner-Valle; A V Clayton; M A McCrae
Journal: J Virol Date: 1982-05 Impact factor: 5.103

1 in total

Mutagenic specificity in reovirus.

1. IDENTIFICATION OF THE ALTERED BASES IN MUTATED SINGLE-STRANDED DNA. I. IN VITRO MUTAGENESIS BY HYDROXYLAMINE, ETHYL METHANESULFONATE AND NITROUS ACID.

2. Reversal of mutant phenotypes by 5-fluorouracil: an approach to nucleotide sequences in messenger-RNA.

3. Production of mutants of tobacco mosaic virus by chemical alteration of its ribonucleic acid in vitro.

4. THE DIFFERENCE BETWEEN SPONTANEOUS AND BASE-ANALOGUE INDUCED MUTATIONS OF PHAGE T4.

5. Local mutagenesis: a method for generating viral mutants with base substitutions in preselected regions of the viral genome.

6. Method for rapidly screening revertants of reovirus temperature-sensitive mutants for extragenic suppression.

7. Proflavin mutagenesis of bacteria.

8. Revertants of temperature-sensitive mutants of reovirus: evidence for frequent extragenic suppression.

9. Isolation and preliminary genetic and biochemical characterization of temperature-sensitive mutants of reovirus.

10. Mutagenesis of super-suppressors in yeast.

1. Molecular biology of rotaviruses. III. Isolation and characterization of temperature-sensitive mutants of bovine rotavirus.