| Literature DB >> 480165 |
R Davis, C H Wells, A R Taylor.
Abstract
Photolytic decomposition of indapamide (I) in nitrogen-flushed methanol yields 3-sulfamoyl-4-chlorobenzamide (II), 2-methylindoline (III), semicarbazide (IV), and 1-(N-formamido)-2-methylindoline (V); in oxygen-flushed methanol, II--V, 1-aminocarboxymethyl-2-methylindoline (VI), 3-sulfamoyl-4-chlorobenzoic acid (VII), methyl-3-sulfamoyl-4-chlorobenzoate (VIII), and 2-(N-acetamido)-benzoic acid (IX) are formed. A comparison is made with thermal decomposition of I.Entities:
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Year: 1979 PMID： 480165 DOI： 10.1002/jps.2600680840
Source DB: PubMed Journal: J Pharm Sci ISSN： 0022-3549 Impact factor: 3.534