Literature DB >> 479930

Intraspinal tumors in children. A review of 81 cases.

A L DeSousa, J E Kalsbeck, J Mealey, R L Campbell, A Hockey.   

Abstract

The authors have presented 81 children with intraspinal tumors, all less than 16 years of age. The clinical features indicated that gait disturbance, pain, and sphincter disturbance are the most prominent complaints. Reflex changes, paralysis, and sensory impairment are the most frequent physical findings. Cerebrospinal fluid protein was recorded in 47 patients and was abnormal in 34. Spine radiography was abnormal in 58% of the patients. Seventy of the patients had myelography, and it was diagnostic in 67. Surgery was performed on 79 patients, with a 2.5% operative mortality (30 days postsurgery). Of the 49 patients who are alive, 91.5% are able to walk. Mean follow-up period was 8.5 years. The authors document the benign course of the intramedullary astrocytomas and suggest an approach to their treatment. They encourage an aggressive approach to metastatic intraspinal tumors. The latrogenic origin of some epidermoid tumors is noted. The importance of early diagnosis and treatment of the intraspinal tumors in children is emphasized.

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Year:  1979        PMID: 479930     DOI: 10.3171/jns.1979.51.4.0437

Source DB:  PubMed          Journal:  J Neurosurg        ISSN: 0022-3085            Impact factor:   5.115


  27 in total

Review 1.  Radiation therapy and the management of intramedullary spinal cord tumors.

Authors:  S R Isaacson
Journal:  J Neurooncol       Date:  2000-05       Impact factor: 4.130

2.  The influence of central review on outcome in malignant gliomas of the spinal cord: the CCG-945 experience.

Authors:  Eric Bouffet; Jeffrey C Allen; James M Boyett; Allen Yates; Floyd Gilles; Peter C Burger; Richard L Davis; Laurence E Becker; Ian F Pollack; Jonathan L Finlay
Journal:  J Neurosurg Pediatr       Date:  2015-12-18       Impact factor: 2.375

3.  Irradiation of pediatric high-grade spinal cord tumors.

Authors:  Rahul D Tendulkar; Atmaram S Pai Panandiker; Shengjie Wu; Larry E Kun; Alberto Broniscer; Robert A Sanford; Thomas E Merchant
Journal:  Int J Radiat Oncol Biol Phys       Date:  2010-03-24       Impact factor: 7.038

4.  Management of pediatric spinal cord astrocytomas: outcomes with adjuvant radiation.

Authors:  Zachary D Guss; Shalini Moningi; George I Jallo; Kenneth J Cohen; Moody D Wharam; Stephanie A Terezakis
Journal:  Int J Radiat Oncol Biol Phys       Date:  2013-02-20       Impact factor: 7.038

5.  The clinical features and surgical outcomes of pediatric patients with primary spinal cord tumor.

Authors:  Gwi Hyun Choi; Jae Keun Oh; Tae Yup Kim; Nam Kyu You; Hyo Sang Lee; Do Heum Yoon; Yoon Ha; Seong Yi; Dong Seok Kim; Joong Uhn Choi; Keung Nyun Kim
Journal:  Childs Nerv Syst       Date:  2012-03-25       Impact factor: 1.475

6.  A dumbbell (hourglass) neurofibroma of the spine in a patient with von Recklinghausen's disease. A case report with twelve-year follow-up.

Authors:  R M Castelein; G D MacEwen
Journal:  Arch Orthop Trauma Surg       Date:  1984

7.  Invasive character of an intradural spinal meningioma in early childhood.

Authors:  D Fournier; P Mercier; F Pouplard; P Menei; G Guy
Journal:  Childs Nerv Syst       Date:  1993-02       Impact factor: 1.475

8.  Spinal cord tumors: gadolinium-DTPA-enhanced MR imaging.

Authors:  M C Chamberlain; A D Sandy; G A Press
Journal:  Neuroradiology       Date:  1991       Impact factor: 2.804

9.  Lumbar epidural Ewing sarcoma. Light and electron microscopic investigation.

Authors:  A Simonati; M Vio; A M Iannucci; A Bricolo; N Rizzuto
Journal:  J Neurol       Date:  1981       Impact factor: 4.849

10.  Primary spinal cord tumors of childhood: effects of clinical presentation, radiographic features, and pathology on survival.

Authors:  John R Crawford; Alejandra Zaninovic; Mariarita Santi; Elisabeth J Rushing; Cara H Olsen; Robert F Keating; Gilbert Vezina; Nadja Kadom; Roger J Packer
Journal:  J Neurooncol       Date:  2009-06-12       Impact factor: 4.130

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