Literature DB >> 479670

Serum amyloid P-component levels in amyloidosis, connective tissue diseases, infection, and malignancy as compared to normal serum.

M Skinner, J L Vaitukaitis, A S Cohen, M D Benson.   

Abstract

A highly sensitive radioimmunoassay was developed to measure the serum levels of SAP. Sera from 50 normal individuals ranging in age from 4 to 89 years had a mean level of 7.47 mg/dl and showed no variations with age. Sera from persons with various clinical types of amyloidosis, connective tissue diseases, and bacterial pneumonia did not differ significantly from normal values. A significant difference was noted in the sera from persons with malignancy, where a mean value of 10.79 mg/dl was determined. Although a number of similarities exist between SAP and CRP, SAP does not share the property of being an acute-phase reactant.

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Year:  1979        PMID： 479670

Source DB:  PubMed          Journal:  J Lab Clin Med        ISSN： 0022-2143


  8 in total

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5.  Metabolic studies of radioiodinated serum amyloid P component in normal subjects and patients with systemic amyloidosis.

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  8 in total

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